| Week | Add | Drop |
| Week 1 |
Round 1: C Yermín Mercedes - ChA Round 2: OF Akil Baddoo - Det | |
| Week 2 |
Round 1: SP Johnny Cueto - SF Round 2: RP Corey Knebel - LAD |
Round 1: RP Anthony Bass - Mia |
| Week 4 |
Round 1: 2B Joey Wendle - TB |
Round 1: C Danny Jansen - Tor |
| Week 5 |
Round 1: SP Madison Bumgarner - Ari |
Round 1: OF Andrew Benintendi - KC |
| Week 6 |
Round 1: RP Rafael Montero - Sea Round 2: OF Hunter Renfroe - Mil |
Round 1: RP Amir Garrett - Cin Round 2: SP J.A. Happ - Min |
| Week 7 |
Round 1: OF Estevan Florial - NYA Round 2: OF Jarren Duran - Bos |
Round 1: RP Corey Knebel - LAD Round 2: SP Dylan Bundy - LAA |
| Week 8 |
Round 1: SP Cody Poteet - Mia |
Round 1: 1B Mitch Moreland - Oak |
| Week 9 |
Round 1: RP Luis Garcia - Hou Round 2: 1B Garrett Cooper - Mia |
Round 1: SP Johnny Cueto - SF Round 2: OF Akil Baddoo - Det |
| Week 10 |
Round 1: 3B Patrick Wisdom - ChN Round 2: SP Vladimir Gutierrez - Cin |
Round 1: RP Rafael Montero - Sea Round 2: SP Madison Bumgarner - Ari |
| Week 11 |
Round 1: RP Lou Trivino - Oak Round 2: 3B Josh Jung - Tex |
Round 1: 1B Garrett Cooper - Mia Round 2: 3B Asdrubal Cabrera - Ari |
| Week 12 |
Round 1: 2B Jonathan India - Cin Round 2: SP Erick Fedde - Was |
Round 1: SP AJ Puk - Oak Round 2: SP Zach Eflin - Phi |
| Week 14 |
Round 1: RP Kyle Muller - Atl Round 2: C Sam Huff - Tex |
Round 1: RP Hector Neris - Phi |
| Week 15 |
Round 1: RP Jacob McGee - SF Round 2: OF Drew Waters - Atl |
Round 1: SP Erick Fedde - Was Round 2: SP Cody Poteet - Mia |
| Week 17 |
Round 1: OF Jasson Dominguez - NYA Round 2: SP Josiah Gray - Was |
Round 1: C Yermín Mercedes - ChA Round 2: SP Vladimir Gutierrez - Cin |
| Week 18 |
Round 2: SS Rodolfo Castro - Pit |
Round 2: OF Hunter Renfroe - Bos |
| Week 20 |
Round 1: SP Luis Gil - NYA Round 2: SP Daulton Jefferies - Oak |
Round 1: SS Rodolfo Castro - Pit Round 2: RP James Karinchak - Cle |
| Week 22 |
Round 1: RP Edward Cabrera - Mia |
Round 1: RP Lou Trivino - Oak |
| 1st Team | 2nd Team |
| Pre-Season | |
| Final Verdict | Brooklyn Cyclones III |
|
3B
Manny Machado
SD OF Kyle Lewis Sea |
OF
Aaron Judge
NYA SS Dansby Swanson Atl |
| Pre-Season | |
| Final Verdict | Revelation |
|
SS
Jorge Polanco
Min |
RP
James Karinchak
Cle |
| Week 11 | |
| Final Verdict | Revelation |
|
SP
Max Scherzer
NYN SS Dansby Swanson Atl OF Dylan Carlson StL |
SS
Carlos Correa
Min C Joey Bart SF 2B Vidal Brujan TB |
| Week 12 | |
| Final Verdict | Horseheads Buffalos |
|
SP
Charlie Morton
Atl |
SP
MacKenzie Gore
SD |