| Week | Add | Drop |
| Week 1 |
Round 1: SP Yusei Kikuchi - Tor Round 2: SP Matt Shoemaker - Min |
Round 2: SP Michael Kopech - ChA |
| Week 2 |
Round 1: RP Emmanuel Clase - Cle Round 2: RP Yimi Garcia - Hou |
Round 2: C Tom Murphy - Sea |
| Week 3 |
Round 1: 1B Travis Shaw - Tor Round 2: C Carson Kelly - Ari | |
| Week 4 |
Round 1: SP Cesar Valdez - Bal Round 2: RP Ian Kennedy - Ari |
Round 2: SP Cesar Valdez - Bal |
| Week 5 |
Round 1: RP Josh Staumont - KC Round 2: 2B Josh Rojas - Ari | |
| Week 6 |
Round 1: SP Tony Gonsolin - LAD | |
| Week 7 |
Round 1: SP Yusei Kikuchi - Tor Round 2: SP Alek Manoah - Tor | |
| Week 8 |
Round 1: OF Ian Happ - ChN Round 2: SS Owen Miller - Cle |
Round 1: RP Emmanuel Clase - Cle Round 2: SP Yusei Kikuchi - Sea |
| Week 9 |
Round 1: 2B Vidal Brujan - TB Round 2: 2B Ty France - Sea |
Round 1: SS Owen Miller - Cle Round 2: 1B Travis Shaw - Tor |
| Week 10 |
Round 1: 2B Jonathan Schoop - Det Round 2: C Ryan Jeffers - Min |
Round 2: RP Ian Kennedy - Phi |
| Week 11 |
Round 1: 3B Jonathan Villar - ChN Round 2: SP Jesus Luzardo - Mia |
Round 1: 2B Keston Hiura - Mil Round 2: SP Jonathan Gray - Col |
| Week 12 |
Round 1: SP Tarik Skubal - Det Round 2: SS J.P. Crawford - Sea |
Round 1: SP Steven Matz - Tor Round 2: 3B Nick Solak - Tex |
| Week 13 |
Round 1: 2B Keston Hiura - Mil Round 2: SP Kendall Graveman - Hou |
Round 1: OF Ian Happ - ChN Round 2: 3B Jonathan Villar - NYN |
| Week 14 |
Round 1: OF Kole Calhoun - Tex Round 2: RP Heath Hembree - NYN | |
| Week 15 |
Round 1: SP Tony Gonsolin - LAD Round 2: SP Logan Webb - SF | |
| Week 17 |
Round 1: SP Tylor Megill - NYN Round 2: SP Madison Bumgarner - Ari |
Round 1: C Ryan Jeffers - Min Round 2: 1B Nathaniel Lowe - Tex |
| Week 18 |
Round 1: SP Miles Mikolas - StL Round 2: SP Jaime Barria - LAA |
Round 1: RP Heath Hembree - Phi |
| Week 19 |
Round 1: SP Cal Quantrill - Cle Round 2: 3B Abraham Toro - Sea |
Round 2: 2B Keston Hiura - Mil |
| Week 20 |
Round 1: 3B Colin Moran - Pit Round 2: OF Sam Hilliard - Col |
Round 1: OF Kole Calhoun - Ari Round 2: SP Jaime Barria - LAA |
| Week 22 |
Round 1: C Connor Joe - Col Round 2: SP Alec Mills - ChN |
Round 2: C Mitch Garver - Min |
| 1st Team | 2nd Team |
| Pre-Season | |
| Revelation | Final Verdict |
|
RP
James Karinchak
Cle |
SS
Jorge Polanco
Min |
| Pre-Season | |
| Revelation | Brooklyn Cyclones III |
|
SP
Triston McKenzie
Cle 3B Bobby Dalbec Bos |
SP
Brandon Woodruff
Mil |
| Week 3 | |
| Revelation | Jacksonville Red Caps |
|
3B
Ryan Mountcastle
Bal |
OF
Ian Happ
ChN |
| Week 11 | |
| Revelation | Final Verdict |
|
SS
Carlos Correa
Min C Joey Bart SF 2B Vidal Brujan TB |
SP
Max Scherzer
NYN SS Dansby Swanson Atl OF Dylan Carlson StL |
| Week 11 | |
| Revelation | Built 4 Speed |
|
OF
Dylan Carlson
StL SP Sixto Sánchez Mia SP Alek Manoah Tor |
SP
Jonathan Gray
Col SP Steven Matz StL OF Tyler O'Neill StL |
| Week 12 | |
| Revelation | Built 4 Speed |
|
SP
Jesus Luzardo
Mia OF Franmil Reyes Cle 2B Ty France Sea SP Tony Gonsolin LAD |
3B
Eduardo Escobar
NYN RP Yimi Garcia Hou SS Tim Anderson ChA RP Raisel Iglesias LAA |
| Week 14 | |
| Revelation | The Plantation |
|
SS
J.P. Crawford
Sea SP Kendall Graveman Hou 1B Jared Walsh LAA |
RP
Mark Melancon
Ari 3B Josh Donaldson NYA RP Edwin Diaz NYN |
| Week 14 | |
| Revelation | Brooklyn Cyclones III |
|
SP
Chris Sale
Bos SP Tyler Glasnow TB OF Randy Arozarena TB |
1B
Max Muncy
LAD 1B Max Muncy LAD |