| Week | Add | Drop |
| Week 1 |
Round 1: 3B Colin Moran - Pit | |
| Week 2 |
Round 1: SP Jonathan Gray - Tex Round 2: 1B Travis Shaw - Tor |
Round 1: OF Franchy Cordero - Bos Round 2: RP Joakim Soria - Ari |
| Week 3 |
Round 2: RP JT Brubaker - Pit |
Round 2: OF Sam Hilliard - Col |
| Week 4 |
Round 1: C Dom Nunez - Col Round 2: C Mike Zunino - TB |
Round 1: C Austin Nola - SD |
| Week 5 |
Round 1: OF Jordan Luplow - TB Round 2: OF Raimel Tapia - Col |
Round 1: SS Willi Castro - Det Round 2: SP Corey Kluber - NYA |
| Week 6 |
Round 1: OF Guillermo Heredia - Atl Round 2: C William Contreras - Atl |
Round 1: OF Victor Robles - Was |
| Week 7 |
Round 1: SS Niko Goodrum - Hou Round 2: SP Justin Dunn - Sea |
Round 1: 1B Ji-Man Choi - TB Round 2: RP Jordan Romano - Tor |
| Week 8 |
Round 1: RP Jacob McGee - SF Round 2: RP Lou Trivino - Oak |
Round 1: OF Jordan Luplow - Cle Round 2: RP Rafael Montero - Sea |
| Week 9 |
Round 1: SP Adbert Alzolay - ChN Round 2: SP Logan Webb - SF |
Round 1: SP Justin Dunn - Sea Round 2: RP JT Brubaker - Pit |
| Week 10 |
Round 1: OF Tommy Pham - Cin Round 2: C Eric Haase - Det |
Round 1: C Dom Nunez - Col Round 2: SP Logan Webb - SF |
| Week 11 |
Round 1: SS Luis Urias - Mil |
Round 1: OF Guillermo Heredia - NYN |
| Week 12 |
Round 1: 2B Danny Mendick - ChA |
Round 1: OF Nick Senzel - Cin |
| Week 13 |
Round 1: 2B Keston Hiura - Mil |
Round 1: 2B Danny Mendick - ChA |
| Week 14 |
Round 1: OF LaMonte Wade Jr - SF |
Round 1: SS Niko Goodrum - Det |
| Week 17 |
Round 1: SP Wily Peralta - Det Round 2: RP Kyle Muller - Atl |
Round 1: SP Adbert Alzolay - ChN Round 2: C William Contreras - Atl |
| Week 19 |
Round 2: OF Rafael Ortega - ChN |
Round 2: OF Kole Calhoun - Ari |
| 1st Team | 2nd Team |
| Week 14 | |
| SWINGIN BLACKJACKS | AMS Power |
|
SS
Jorge Polanco
Min |
OF
Lourdes Gurriel
Tor |
| Week 15 | |
| SWINGIN BLACKJACKS | Fightin Phils |
|
SP
Dylan Cease
ChA |
SP
Luis Severino
NYA |