| Week | Add | Drop |
| Pre-Season |
Round 1: OF Mickey Moniak - LAA |
Round 1: OF Dylan Carlson - StL |
| Week 1 |
Round 1: SP Brady Singer - KC Round 2: 3B Ezequiel Duran - Tex |
Round 2: SP Jose Quintana - NYN |
| Week 2 |
Round 1: SP Yariel Rodriguez - Tor Round 2: SP Christian Scott - NYN |
Round 1: 3B Ezequiel Duran - Tex |
| Week 3 |
Round 1: OF Emmanuel Rodriguez - Min Round 2: SP Mike Lorenzen - Tex |
Round 2: SP Tyler Wells - Bal |
| Week 4 |
Round 1: RP Kirby Yates - Tex Round 2: 1B Ryan O'Hearn - Bal |
Round 2: SP AJ Puk - Mia |
| Week 5 |
Round 1: SS Jordan Lawlar - Ari Round 2: RP Felix Bautista - Bal | |
| Week 6 |
Round 1: SP Taj Bradley - TB Round 2: 2B Luis Arraez - SD |
Round 1: SP Yariel Rodriguez - Tor Round 2: 2B Whit Merrifield - Phi |
| 1st Team | 2nd Team |
| Pre-Season | |
| Fightin Phils | Chiraq Villains |
|
3B
Ke'Bryan Hayes
Pit |
OF
Byron Buxton
Min |
| Pre-Season | |
| Fightin Phils | Vegas Green and Gold |
|
3B
Royce Lewis
Min |
OF
Evan Carter
Tex |
| Pre-Season | |
| Fightin Phils | Orvon 26 |
|
Round 1, 10th Pick (SP Tanner Bibee Cle) |
SP
Braxton Garrett
Mia |
| Pre-Season | |
| Fightin Phils | Vegas Green and Gold |
|
Round 2, 10th Pick (OF Tyler O'Neill Bos) Round 3, 10th Pick (SP Ryan Pepiot TB) |
SS
Oneil Cruz
Pit Round 16, 9th Pick (SP Jose Quintana NYN) Round 18, 9th Pick (3B J.D. Davis Oak) |
| Week 5 | |
| Fightin Phils | Vegas Green and Gold |
|
RP
Evan Phillips
LAD SP Pablo Lopez Min |
SP
Ryan Weathers
Mia SP Spencer Strider Atl |
| Week 5 | |
| Fightin Phils | Bronx Zoo |
|
SP
Justin Verlander
Hou DH J.D. Martinez NYN SP Yu Darvish SD RP Kirby Yates Tex 2B Bryson Stott Phi 3B Maikel Garcia KC |
OF
Charlie Blackmon
Col 2B Whit Merrifield Phi 1B Joey Meneses Was 2B Matt McLain Cin RP Abner Uribe Mil SP Logan Allen Cle |