| Week | Add | Drop |
| Pre-Season |
Round 1: SP Yusei Kikuchi - Tor Round 2: SP Tyler Wells - Bal Round A: SP Ryan Pepiot - TB Round B: OF Hunter Goodman - Col |
Round 1: SP Eduardo Rodriguez - Ari Round 2: SP Trevor Bauer - LAD Round A: C Endy Rodriguez - Pit Round B: 1B LaMonte Wade Jr - SF |
| Week 1 |
Round 1: RP Jason Foley - Det Round 2: SS Oswaldo Cabrera - NYA | |
| Week 2 |
Round 1: SP Reynaldo Lopez - Atl Round 2: SS Colson Montgomery - ChA |
Round 2: SP Tyler Wells - Bal |
| Week 3 |
Round 1: OF Edward Olivares - Pit Round 2: 2B Thairo Estrada - SF |
Round 1: OF Walker Jenkins - Min Round 2: 2B Brandon Lowe - TB |
| Week 4 |
Round 1: 1B Ryan O'Hearn - Bal Round 2: OF Roman Anthony - Bos |
Round 1: SS Colson Montgomery - ChA Round 2: 1B Carlos Santana - Min |
| Week 5 |
Round 1: SP Mitchell Parker - Was Round 2: SS Tyler Freeman - Cle |
Round 1: OF Edward Olivares - Pit Round 2: DH Mitch Garver - Sea |
| Week 6 |
Round 1: 2B Luis Rengifo - LAA Round 2: 1B Tyler Nevin - Oak |
Round 2: SS Tyler Freeman - Cle |
| 1st Team | 2nd Team |
| Pre-Season | |
| Don Mattingly | Bad Reputation |
|
Round 7, 3rd Pick (SP Yu Darvish SD) |
SP
Chris Sale
Atl |
| Pre-Season | |
| Don Mattingly | Natural Grass |
|
Round 5, 3rd Pick (SP Zach Eflin TB) |
OF
Eloy Jimenez
ChA |
| Pre-Season | |
| Don Mattingly | Natural Grass |
|
2B
Ozzie Albies
Atl OF Michael Harris Atl OF Jackson Chourio Mil |
1B
Freddie Freeman
LAD Round 15, 7th Pick (OF Walker Jenkins Min) Round 19, 7th Pick |
| Pre-Season | |
| Don Mattingly | Fort Worth Panthers |
|
SP
Chris Sale
Atl |
Round 11, 1st Pick (SP Hunter Brown Hou) |
| Pre-Season | |
| Don Mattingly | San Francisco Sea Lions |
|
OF
Eloy Jimenez
ChA OF Jarred Kelenic Atl OF James Wood Was |
SS
Anthony Volpe
NYA Round 10, 10th Pick (OF Nelson Velazquez KC) |
| Pre-Season | |
| Don Mattingly | Irish Panthers |
|
RP
Kendall Graveman
Hou |
Round 8, 11th Pick (SS Ha-seong Kim SD) |
| Week 3 | |
| Don Mattingly | Fort Worth Panthers |
|
SP
Gerrit Cole
NYA RP Griffin Jax Min |
RP
Edwin Diaz
NYN SP Kutter Crawford Bos |
| Week 6 | |
| Don Mattingly | San Francisco Sea Lions |
|
2B
Xander Bogaerts
SD SP Cristopher Sanchez Phi OF Jasson Dominguez NYA SS Anthony Volpe NYA |
RP
Kirby Yates
Tex 2B Jordan Westburg Bal |