| Week | Add | Drop |
| Pre-Season |
Round 1: SS Max Muncy - Oak Round A: 2B Kristian Campbell - Bos Round B: OF Walker Jenkins - Min |
Round A: C Bo Naylor - Cle Round B: RP Kenley Jansen - LAA |
| Week 1 |
Round 1: C Sean Murphy - Atl Round 2: SP Drew Rasmussen - TB Round 3: 2B Tyler Fitzgerald - SF | |
| Week 2 |
Round 2: C Connor Wong - Bos | |
| Week 3 |
Round 1: 3B Noelvi Marte - Cin Round 2: 2B Hyeseong Kim - LAD Round 3: 1B Rhys Hoskins - Mil |
Round 1: 2B Tyler Fitzgerald - SF Round 2: 3B Noelvi Marte - Cin Round 3: SS Max Muncy - Oak |
| Week 4 |
Round 2: RP Tommy Kahnle - Det |
Round 2: 3B Ke'Bryan Hayes - Pit |
| Week 5 |
Round 1: SP Clayton Kershaw - LAD Round 2: SP Hayden Wesneski - Hou Round 3: SP Jeffrey Springs - Oak |
Round 1: 2B Hyeseong Kim - LAD Round 3: RP Tommy Kahnle - Det |
| Week 6 |
Round 1: 2B Christian Moore - LAA |
Round 1: SP Jeffrey Springs - Oak |
| 1st Team | 2nd Team |
| Pre-Season | |
| Six 2 Four 2 Three | Ridley |
|
SP
Carlos Rodon
NYA 2B Kristian Campbell Bos |
C
Adley Rutschman
Bal 3B Coby Mayo Bal |
| Pre-Season | |
| Six 2 Four 2 Three | Ridley |
|
Round 5, 7th Pick (OF Kerry Carpenter Det) |
SP
George Kirby
Sea Round 19, 2nd Pick (C Connor Wong Bos) |
| Week 4 | |
| Six 2 Four 2 Three | Ridley |
|
RP
Ryan Pressly
ChN SP Brandon Pfaadt Ari |
2B
Marcus Semien
Tex OF Dylan Crews Was |