| Week | Add | Drop |
| Pre-Season |
Round 1: 3B Oliver Dunn - Mil Round A: SS Sebastian Walcott - Tex Round B: 2B Hyeseong Kim - LAD |
Round A: 1B Deyvison De Los Santos - Mia |
| Week 1 |
Round 1: SP Sean Burke - ChA Round 2: 3B Ernie Clement - Tor Round 3: OF Victor Scott - StL | |
| Week 2 |
Round 1: RP Dennis Santana - Pit Round 2: SP Griffin Canning - NYN Round 3: SP Chad Patrick - Mil |
Round 1: 3B Oliver Dunn - Mil Round 2: SP Sean Burke - ChA Round 3: 3B Ernie Clement - Tor |
| Week 3 |
Round 1: OF Sal Frelick - Mil Round 3: 3B Dylan Moore - Sea |
Round 1: 3B Matt Vierling - Det Round 3: SP Chad Patrick - Mil |
| Week 4 |
Round 1: SS Kyle Farmer - Col Round 3: SP Clarke Schmidt - NYA |
Round 1: RP Dennis Santana - Pit Round 3: SS Brayan Rocchio - Cle |
| Week 5 |
Round 2: OF Alex Verdugo - Atl |
Round 2: SS Kyle Farmer - Col |
| Week 6 |
Round 2: SS Javier Baez - Det |
Round 2: OF Sal Frelick - Mil |
| 1st Team | 2nd Team |
| Pre-Season | |
| Tennessee Rats | The Plantation |
|
OF
Brenton Doyle
Col |
Round 6, 7th Pick (SP Bailey Ober Min) |
| Pre-Season | |
| Tennessee Rats | Midnight Run |
|
3B
Mark Vientos
NYN 1B Christian Encarnacion-Strand Cin |
OF
Jackson Chourio
Mil Round 7, 8th Pick (SS Jeremy Pena Hou) |
| Pre-Season | |
| Tennessee Rats | Deputy Dawg |
|
OF
Oneil Cruz
Pit |
SS
Bo Bichette
Tor |
| Pre-Season | |
| Tennessee Rats | Hulmeville Hot Shots |
|
Round 2, 6th Pick (3B Connor Norby Mia) |
SP
Yoshinobu Yamamoto
LAD |
| Pre-Season | |
| Tennessee Rats | Deputy Dawg |
|
Round 3, 6th Pick (3B Nolan Arenado StL) |
SP
Spencer Strider
Atl |
| Pre-Season | |
| Tennessee Rats | At My Witt's End |
|
Round 1, 9th Pick (SP Hunter Greene Cin) Round 5, 9th Pick (SP Luis Castillo Sea) |
SP
Chris Sale
Atl |