| Week | Add | Drop |
| Pre-Season |
Round A: SP Yoshinobu Yamamoto - LAD Round B: SP Kyle Harrison - SF |
Round A: 1B Garrett Cooper - Bos |
| Week 3 |
Round 1: OF Edward Olivares - Pit Round 2: OF Brandon Marsh - Phi | |
| Week 4 |
Round 1: 3B Josh Smith - Tex Round 2: 1B LaMonte Wade Jr - SF |
Round 2: 2B Davis Schneider - Tor |
| Week 5 |
Round 1: SP Keaton Winn - SF Round 2: SP Emerson Hancock - Sea |
Round 1: SS Trevor Story - Bos Round 2: 1B Jose Abreu - Hou |
| Week 6 |
Round 1: OF Mike Tauchman - ChN Round 2: OF Dylan Carlson - StL |
Round 1: OF Kerry Carpenter - Det Round 2: OF Edward Olivares - Pit |
| Week 7 |
Round 1: SP Robert Gasser - Mil Round 2: SP Erick Fedde - ChA |
Round 1: SP Emerson Hancock - Sea Round 2: SP Aaron Civale - TB Round 2: OF TJ Friedl - Cin |
| 1st Team | 2nd Team |
| Pre-Season | |
| Deputy Dawg | Will Clark |
|
SP
Grayson Rodriguez
Bal |
OF
Spencer Steer
Cin |
| Pre-Season | |
| Deputy Dawg | Hit for the Cycle |
|
Round 9, 1st Pick (OF Jung Hoo Lee SF) |
SP
Lucas Giolito
Bos |
| Pre-Season | |
| Deputy Dawg | Hit for the Cycle |
|
Round 6, 1st Pick (SP Gavin Williams Cle) |
SP
Logan Gilbert
Sea |
| Pre-Season | |
| Deputy Dawg | Wasco Reserve |
|
OF
Jasson Dominguez
NYA SP Bobby Miller LAD |
RP
Josh Hader
Hou |
| Pre-Season | |
| Deputy Dawg | Fightin Phils |
|
C
Elias Diaz
Col |
Round 4, 10th Pick (2B Jorge Polanco Sea) |
| Pre-Season | |
| Deputy Dawg | Will Clark |
|
C
Gabriel Moreno
Ari |
Round 4, 2nd Pick (1B Jose Abreu Hou) |
| Pre-Season | |
| Deputy Dawg | Will Clark |
|
SS
Geraldo Perdomo
Ari |
Round 13, 2nd Pick (C Kyle Teel Bos) |
| Pre-Season | |
| Deputy Dawg | Will Clark |
|
Round 8, 1st Pick (SP Jose Berrios Tor) |
SP
Grayson Rodriguez
Bal |
| Pre-Season | |
| Deputy Dawg | Heeeeeeeeere's Johnny |
|
OF
Corbin Carroll
Ari |
1B
Vladimir Guerrero Jr
Tor |
| Pre-Season | |
| Deputy Dawg | 35 GAMERS. |
|
3B
Royce Lewis
Min |
DH
Marcell Ozuna
Atl Round 4, 6th Pick (SP Kyle Harrison SF) |
| Pre-Season | |
| Deputy Dawg | Will Clark |
|
2B
Matt McLain
Cin |
SS
Anthony Volpe
NYA Round 2, 2nd Pick (RP Raisel Iglesias Atl) |
| Week 5 | |
| Deputy Dawg | Sweetness |
|
SP
Grayson Rodriguez
Bal |
OF
Adolis Garcia
Tex |
| Week 5 | |
| Deputy Dawg | Heeeeeeeeere's Johnny |
|
1B
Vladimir Guerrero Jr
Tor SP Yoshinobu Yamamoto LAD |
1B
Josh Naylor
Cle OF Colton Cowser Bal |
| Week 7 | |
| Deputy Dawg | 35 GAMERS. |
|
RP
Josh Hader
Hou |
OF
Jordan Walker
StL |