| Week | Add | Drop |
| Week 1 |
Round 1: C Elias Diaz - Col Round 2: OF Alek Thomas - Ari | |
| Week 3 |
Round 1: 3B Josh Smith - Tex Round 2: OF Brandon Marsh - Phi | |
| Week 5 |
Round 1: SP Jack Leiter - Tex Round 2: SP Bryce Elder - Atl |
Round 1: SP Julio Urías - F/A |
| Week 6 |
Round 1: OF Jurickson Profar - SD |
Round 1: OF Jose Siri - TB |
| 1st Team | 2nd Team |
| Pre-Season | |
| Philly Cheesesteaks | Gregg Olson's Yakker |
|
SP
Jonathan Gray
Tex 1B Peter Alonso NYN SP Quinn Priester Pit OF Chas McCormick Hou |
SP
Max Fried
Atl OF Eloy Jimenez ChA SP Brayan Bello Bos SP Eury Perez Mia |
| Pre-Season | |
| Philly Cheesesteaks | Winning is Contagious |
|
SP
Eury Perez
Mia |
SP
Framber Valdez
Hou OF Spencer Steer Cin |
| Pre-Season | |
| Philly Cheesesteaks | Bottom of the pack 99 |
|
SP
Zach Eflin
TB |
SP
Nick Lodolo
Cin |
| Pre-Season | |
| Philly Cheesesteaks | Sam Anderson |
|
SP
Blake Snell
SF 3B Alec Bohm Phi |
3B
Yoan Moncada
ChA Round 1, 1st Pick (SP Yoshinobu Yamamoto LAD) |
| Pre-Season | |
| Philly Cheesesteaks | Bing's Bastards |
|
OF
Lars Nootbaar
StL |
OF
Nick Castellanos
Phi |
| Week 2 | |
| Philly Cheesesteaks | Sam Anderson |
|
SS
J.P. Crawford
Sea SP Brayan Bello Bos |
SS
Anthony Volpe
NYA |
| Week 4 | |
| Philly Cheesesteaks | Winning is Contagious |
|
SS
Bo Bichette
Tor OF Spencer Steer Cin |
C
Joey Bart
Pit 3B Gunnar Henderson Bal 2B Edouard Julien Min |
| Week 5 | |
| Philly Cheesesteaks | Mike Krupa |
|
SP
Yu Darvish
SD 3B Nolan Arenado StL |
SP
Seth Lugo
KC 1B Nate Lowe Tex |