| Week | Add | Drop |
| Pre-Season |
Round 1: SS Tyler Freeman - Col | |
| Week 1 |
Round 1: 1B Jeimer Candelario - Cin Round 2: SP Zack Littell - TB Round 3: SP Yusei Kikuchi - LAA |
Round 1: SS Tyler Freeman - Col Round 3: SP Zack Littell - TB |
| Week 2 |
Round 1: RP Dennis Santana - Pit Round 2: 2B Michael Massey - KC |
Round 2: 1B Jeimer Candelario - Cin |
| Week 3 |
Round 1: SP JP Sears - Oak Round 2: C Danny Jansen - TB Round 3: 3B Chase Meidroth - ChA |
Round 1: SP Spencer Arrighetti - Hou Round 2: C Miguel Amaya - ChN Round 3: RP Dennis Santana - Pit |
| Week 4 |
Round 1: SP Eduardo Rodriguez - Ari Round 2: SP Hayden Wesneski - Hou Round 3: SS Jordan Lawlar - Ari |
Round 1: 2B Michael Massey - KC Round 2: 3B Chase Meidroth - ChA Round 3: SP Hayden Wesneski - Hou |
| Week 5 |
Round 1: SS Jose Caballero - TB Round 2: C Miguel Amaya - ChN |
Round 1: SP Max Scherzer - Tor Round 2: C Danny Jansen - TB |
| Week 6 |
Round 1: SP Tanner Houck - Bos Round 2: SP Justin Verlander - SF |
Round 1: SP Eduardo Rodriguez - Ari Round 2: SP Yusei Kikuchi - LAA |
| 1st Team | 2nd Team |