| Week | Add | Drop |
| Pre-Season |
Round 1: RP Dellin Betances - NYA Round A: 3B Miguel Andújar - NYA |
Round A: OF Ben Gamel - Sea |
| Week 1 |
Round 1: SP Tyler Mahle - Cin Round 2: C James McCann - Det |
Round 2: SS Jorge Polanco - Min |
| Week 2 |
Round 1: SP Zack Wheeler - NYN Round 2: OF Jurickson Profar - Tex |
Round 1: RP Dellin Betances - NYA Round 2: DH Evan Gattis - Hou |
| Week 3 |
Round 1: OF Teoscar Hernández - Tor Round 2: 1B Ryan McMahon - Col |
Round 1: OF Micahel Taylor - Was Round 2: 3B Brandon Drury - Tor |
| Week 4 |
Round 1: OF Mallex Smith - TB Round 2: RP Addison Reed - Min |
Round 1: SP Tyler Mahle - Cin Round 2: OF Nick Williams - Phi |
| Week 5 |
Round 1: SP Nick Kingham - Pit |
Round 1: SP Lance Lynn - NYA |
| Week 6 |
Round 1: RP Matt Koch - Ari |
Round 1: RP Addison Reed - Min |
| Week 7 |
Round 1: SP Freddy Peralta - Mil Round 2: 2B Robinson Cano - NYN |
Round 1: SP Zack Wheeler - NYN Round 2: 2B Kolten Wong - StL |
| Week 8 |
Round 2: RP José Alvarado - TB |
Round 2: RP Alex Colome - Sea |
| Week 9 |
Round 2: 1B Max Muncy - LAD |
Round 2: OF Mallex Smith - TB |
| Week 10 |
Round 1: OF Niko Goodrum - Det Round 2: SP Germán Márquez - Col |
Round 1: SP Nick Kingham - Pit Round 2: RP José Alvarado - TB |
| Week 11 |
Round 1: SP Dylan Covey - ChA |
Round 1: SP Freddy Peralta - Mil |
| Week 12 |
Round 1: SP Freddy Peralta - Mil Round 2: SP Tyler Mahle - Cin |
Round 2: SP Germán Márquez - Col |
| Week 13 |
Round 1: C Austin Romine - NYA Round 2: SP Lucas Giolito - ChA |
Round 1: C James McCann - Det Round 2: RP Matt Koch - Ari |
| Week 14 |
Round 1: SS Amed Rosario - NYN Round 2: OF Stephen Piscotty - Oak |
Round 1: SS Orlando Arcia - Mil Round 2: SP Lucas Giolito - ChA |
| Week 15 |
Round 1: OF Nick Williams - Phi Round 2: C Elias Diaz - Pit |
Round 1: OF Alex Verdugo - LAD Round 2: C Brian McCann - Hou |
| Week 17 |
Round 1: SP Daniel Poncedeleon - StL Round 2: C Mitch Garver - Min |
Round 1: SP Dylan Covey - ChA Round 2: C Elias Diaz - Pit |
| Week 18 |
Round 1: DH Evan Gattis - Hou Round 2: SP Wily Peralta - KC |
Round 1: SP Tyler Mahle - Cin Round 2: 1B Ryan McMahon - Col |
| 1st Team | 2nd Team | Votes |
| Week 3 | ||
| Basket Case | Palm Beach Cardinals | Decision |
|
SP
Felix Hernandez
Sea |
SP
Julio Teheran
Atl |
Approved 19-0. See Breakdown |
| Week 5 | ||
| Basket Case | Palm Beach Cardinals | Decision |
|
SP
Jon Lester
ChN |
OF
Alex Verdugo
LAD |
Approved 19-0. See Breakdown |
| Week 5 | ||
| Basket Case | Maine Black Bears | Decision |
|
1B
Eric Hosmer
SD SP Jordan Montgomery NYA |
OF
Ian Desmond
Col SS Corey Seager LAD |
Approved 19-0. See Breakdown |
| Week 11 | ||
| Basket Case | Mama's Boys | Decision |
|
2B
D.J. LeMahieu
Col 1B Max Muncy LAD |
3B
Miguel Sano
Min |
Approved 9-7. See Breakdown |