| Week | Add | Drop |
| Pre-Season |
Round 1: RP Felix Bautista - Bal Round 2: SP Jordan Hicks - SF Round A: SP Yoshinobu Yamamoto - LAD Round B: OF Druw Jones - Ari Round C: C Ethan Salas - SD |
Round A: C Endy Rodriguez - Pit |
| Week 1 |
Round 1: RP Jason Foley - Det Round 2: RP Ronel Blanco - Hou |
Round 1: RP Alex Lange - Det |
| Week 2 |
Round 1: SP Michael Wacha - KC Round 2: OF Heston Kjerstad - Bal |
Round 1: SP Tyler Wells - Bal Round 2: OF Parker Meadows - Det |
| Week 3 |
Round 1: OF Edward Olivares - Pit Round 2: 3B Abraham Toro - Oak |
Round 2: OF Ceddanne Rafaela - Bos Round 2: SP Jesus Luzardo - Mia |
| Week 4 |
Round 1: SS Jose Caballero - TB Round 2: SP Jameson Taillon - ChN |
Round 2: SP Luis Gil - NYA |
| Week 5 |
Round 1: SS Amed Rosario - TB Round 2: 2B Vaughn Grissom - Bos |
Round 1: OF Edward Olivares - Pit Round 2: 3B Abraham Toro - Oak |
| Week 6 |
Round 1: OF Jurickson Profar - SD Round 2: SP Taj Bradley - TB |
Round 1: 2B Colt Keith - Det Round 2: SP Michael Wacha - KC |
| Week 7 |
Round 1: RP Yennier Cano - Bal Round 2: OF Leody Taveras - Tex |
Round 1: RP Jason Foley - Det Round 2: 2B Vaughn Grissom - Bos |
| 1st Team | 2nd Team |
| Pre-Season | |
| Bad Reputation | Ground Rule Double |
|
OF
Wyatt Langford
Tex |
SP
Zac Gallen
Ari |
| Pre-Season | |
| Bad Reputation | Blue Jays |
|
Round 6, 1st Pick (SP Bailey Ober Min) |
SP
Blake Snell
SF |