| Week | Add | Drop |
| Pre-Season |
Round 1: RP Kenley Jansen - Bos | |
| Week 1 |
Round 1: SP Brandon Pfaadt - Ari Round 2: 3B Ezequiel Duran - Tex | |
| Week 2 |
Round 1: 1B Alex Kirilloff - Min Round 2: 3B Jared Triolo - Pit |
Round 2: 3B Ezequiel Duran - Tex |
| Week 3 |
Round 1: OF Edward Olivares - Pit Round 2: SP Cody Poteet - NYA |
Round 1: 1B Ryan Noda - Oak Round 2: OF Walker Jenkins - Min |
| Week 4 |
Round 1: 1B Ryan O'Hearn - Bal Round 2: OF Roman Anthony - Bos |
Round 1: OF Edward Olivares - Pit Round 2: SP Cody Poteet - NYA |
| Week 5 |
Round 1: 2B Rob Refsnyder - Bos Round 2: 2B Josh Rojas - Sea |
Round 1: 3B Jared Triolo - Pit Round 2: OF Jose Siri - TB |
| Week 6 |
Round 1: SP Luis Gil - NYA Round 2: OF Max Kepler - Min |
Round 1: SP Brandon Pfaadt - Ari Round 2: SP Dane Dunning - Tex |
| Week 7 |
Round 1: OF Tommy Pham - ChA |
Round 1: 1B Alex Kirilloff - Min |
| 1st Team | 2nd Team |
| Pre-Season | |
| Ron Guidry | Las Vegas 51's |
|
OF
Wyatt Langford
Tex Round 5, 7th Pick (RP Paul Sewald Ari) |
SS
Bo Bichette
Tor Round 18, 12th Pick (OF Nelson Velazquez KC) |