| Week | Add | Drop |
| Pre-Season |
Round 1: OF Brent Rooker - Oak Round 2: SP Jordan Hicks - SF Round A: SP Kyle Harrison - SF |
Round A: SP Jordan Hicks - SF |
| Week 1 |
Round 1: 3B J.D. Davis - Oak Round 2: SS Jeremy Pena - Hou |
Round 2: SP Tyler Wells - Bal |
| Week 2 |
Round 1: OF Heston Kjerstad - Bal Round 2: OF Connor Joe - Pit |
Round 1: OF Parker Meadows - Det Round 2: SP Casey Mize - Det |
| Week 3 |
Round 1: OF Joey Loperfido - Hou Round 2: 2B Jeff McNeil - NYN |
Round 2: SP Hunter Brown - Hou |
| Week 4 |
Round 1: OF Andy Pages - LAD Round 2: RP Joel Payamps - Mil |
Round 1: 1B Jose Abreu - Hou Round 2: OF Ceddanne Rafaela - Bos |
| Week 5 |
Round 1: SP Bryce Elder - Atl Round 2: 2B Vaughn Grissom - Bos |
Round 1: SP Jesus Luzardo - Mia Round 2: SP Luis Gil - NYA |
| Week 6 |
Round 1: OF Jordan Beck - Col Round 2: SP John Means - Bal |
Round 1: RP Joel Payamps - Mil Round 2: 2B Jeff McNeil - NYN |
| 1st Team | 2nd Team |
| Pre-Season | |
| Bad Reputation | Pirates |
|
Round 6, 4th Pick (C Logan O'Hoppe LAA) |
SP
Blake Snell
SF |