| Week | Add | Drop |
| Pre-Season |
Round 1: SP Clayton Kershaw - LAD |
Round 1: SP Chuck James - Atl |
| Week 1 |
Round 1: SP Dave Bush - Mil Round 2: SP Boof Bonser - Min | |
| Week 2 |
Round 2: 1B Kevin Millar - Bal |
Round 2: SP Dave Bush - Mil |
| Week 5 |
Round 1: RP Brian Wilson - SF Round 2: SP Tim Wakefield - Bos |
Round 2: 1B Dmitri Young - Was Round 2: RP Rafael Soriano - Atl |
| Week 6 |
Round 1: SP Daniel Cabrera - Bal Round 2: OF David Murphy - Tex |
Round 1: SP Carlos Villanueva - Mil Round 2: 1B Kevin Millar - Bal |
| Week 7 |
Round 1: OF Mark Kotsay - Atl Round 2: SP Paul Byrd - Cle |
Round 1: SP Kevin Millwood - Tex Round 2: SP Boof Bonser - Min |
| Week 8 |
Round 1: SS Omar Vizquel - SF |
Round 1: SS Yuniesky Betancourt - Sea |
| Week 9 |
Round 1: SP Bronson Arroyo - Cin Round 2: OF Randy Winn - SF |
Round 1: SP Paul Byrd - Bos Round 2: OF Mark Kotsay - Atl |
| Week 10 |
Round 1: OF Mark Teahen - KC Round 2: SS Yuniesky Betancourt - Sea |
Round 1: SP John Smoltz - Bos Round 2: SS Omar Vizquel - SF Round 2: C Ronny Paulino - Pit |
| Week 12 |
Round 2: OF Randy Winn - SF | |
| Week 13 |
Round 1: SP Kevin Millwood - Tex Round 2: SP Gil Meche - KC |
Round 2: SP Bronson Arroyo - Cin |
| Week 14 |
Round 1: C Ramon Hernandez - Bal |
Round 1: SP Brett Myers - Phi |
| Week 15 |
Round 2: SP Paul Maholm - Pit |
Round 2: OF Mark Teahen - KC |
| Week 17 |
Round 1: SP Brett Myers - Phi |
Round 1: SP Clayton Kershaw - LAD Round 2: C Ramon Hernandez - Bal Round 2: SP Daniel Cabrera - Bal |
| Week 18 |
Round 1: RP Salomon Torres - Mil |
Round 1: SP Kevin Millwood - Tex |
| Week 19 |
Round 1: OF Marlon Byrd - Tex Round 2: SP Bronson Arroyo - Cin |
| 1st Team | 2nd Team | Votes |
| Week 7 | ||
| Quad Cities River Bandits | Las Vegas 51's | Decision |
|
OF
Corey Hart
Mil SP Justin Verlander Det |
OF
Rick Ankiel
StL SP John Maine NYN |
Approved 21-1. See Breakdown |