| Week | Add | Drop |
| Pre-Season |
Round A: RP Tom Wilhelmsen - Sea Round B: RP Brandon League - LAD Round C: SP Johan Santana - NYN |
Round A: C A.J. Elllis - LAD |
| Week 1 |
Round 1: SP Justin Masterson - Cle | |
| Week 2 |
Round 1: OF A.J. Pollock - Ari Round 2: C Nick Hundley - SD |
Round 1: OF Leonys Martin - Tex Round 2: C Russell Martin - Pit |
| Week 3 |
Round 1: RP Jose Quintana - ChA Round 2: RP Joaquin Benoit - Det |
Round 2: OF David Murphy - Tex |
| Week 4 |
Round 1: RP Steve Cishek - Mia Round 2: 1B Carlos Pena - Hou |
Round 1: RP Joaquin Benoit - Det Round 2: DH Adam Lind - Tor Round 2: SS Brendan Ryan - Sea |
| Week 5 |
Round 1: OF Matt Joyce - TB |
Round 1: OF A.J. Pollock - Ari Round 2: SP Brandon McCarthy - Ari |
| Week 6 |
Round 1: SP Zach McAllister - Cle |
Round 1: RP Joel Hanrahan - Bos |
| Week 7 |
Round 1: SP Jonathan Pettibone - Phi Round 2: RP Brandon League - LAD |
Round 2: RP Steve Cishek - Mia |
| Week 8 |
Round 1: OF Seth Smith - Oak Round 2: C Chris Iannetta - LAA |
Round 1: OF Shane Victorino - Bos Round 2: C Nick Hundley - SD |
| Week 9 |
Round 1: OF Mark DeRosa - Tor |
Round 1: RP Brandon League - LAD |
| Week 10 |
Round 1: SS Yuniesky Betancourt - Mil |
Round 1: OF Mark DeRosa - Tor |
| Week 11 |
Round 1: RP Jose Veras - Det Round 2: RP Rex Brothers - Col |
Round 1: RP Rafael Betancourt - Col Round 2: SP Zach McAllister - Cle |
| Week 12 |
Round 1: RP Bobby Parnell - NYN Round 2: RP Miguel Gonzalez - Bal |
Round 2: SP Jonathan Pettibone - Phi |
| Week 13 |
Round 1: SP Alexander Cobb - TB Round 2: OF Michael Brantley - Cle |
Round 1: RP Rex Brothers - Col |
| Week 14 |
Round 1: RP Rafael Betancourt - Col Round 2: OF Alfonso Soriano - NYA |
Round 1: OF Michael Brantley - Cle Round 2: RP Jose Veras - ChN |
| Week 15 |
Round 1: SP Wei-Yin Chen - Bal Round 2: SP Felix Doubront - Bos |
Round 1: RP Miguel Gonzalez - Bal Round 2: OF Seth Smith - Oak |
| Week 17 |
Round 1: OF Norichika Aoki - Mil Round 2: C Ryan Doumit - Min |
Round 1: 1B Carlos Pena - Hou Round 2: SP Paul Maholm - Atl |
| Week 18 |
Round 1: SP Ubaldo Jimenez - Cle Round 2: 3B Matt Dominguez - Hou |
Round 1: C Chris Iannetta - LAA Round 2: SS Yuniesky Betancourt - Mil Round 2: RP Jose Quintana - ChA Round 2: SP Yovani Gallardo - Mil |
| Week 19 |
Round 1: RP Jim Henderson - Mil Round 2: OF Andre Ethier - LAD |
Round 1: 3B Matt Dominguez - Hou Round 2: 1B Mark Reynolds - NYA |
| Week 21 |
Round 1: 3B Alex Rodriguez - NYA Round 2: RP Chris Perez - Cle |
Round 1: RP Bobby Parnell - NYN Round 2: SP Jake Westbrook - StL |
| Week 23 |
Round 1: OF Angel Pagan - SF |
Round 1: RP Rafael Betancourt - Col |
| 1st Team | 2nd Team | Votes |