| Week | Add | Drop |
| Pre-Season |
Round 1: SP Richard Fitts - Bos Round 3: SP Charlie Morton - Bal Round A: SP Eury Perez - Mia |
Round 1: RP Alexis Diaz - Cin Round A: OF Alek Thomas - Ari |
| Week 1 |
Round 1: SS Max Muncy - Oak Round 2: SP Max Meyer - Mia Round 3: SP Kris Bubic - KC |
Round 1: SP Charlie Morton - Bal Round 3: SP Richard Fitts - Bos |
| Week 2 |
Round 1: RP Tommy Kahnle - Det Round 2: OF Zac Veen - Col Round 3: RP José Alvarado - Phi |
Round 1: RP Jordan Romano - Phi Round 2: SS Max Muncy - Oak Round 3: RP Tommy Kahnle - Det |
| Week 3 |
Round 1: SP Tyler Mahle - Tex Round 2: 3B Chase Meidroth - ChA Round 3: SP Shane Smith - ChA |
Round 2: 3B Coby Mayo - Bal Round 3: SP Zach Eflin - Bal |
| Week 4 |
Round 1: 3B Caleb Durbin - Mil Round 2: RP Tommy Kahnle - Det Round 3: C Agustin Ramirez - Mia |
Round 2: SP Shane Smith - ChA Round 2: 3B Chase Meidroth - ChA Round 3: C Gabriel Moreno - Ari |
| Week 5 |
Round 1: OF Jordan Beck - Col Round 2: 1B Eric Wagaman - Mia Round 3: C Edgar Quero - ChA |
Round 1: OF Zac Veen - Col Round 2: RP Tommy Kahnle - Det Round 2: 1B Colt Keith - Det Round 3: C Patrick Bailey - SF |
| Week 6 |
Round 1: SP Lucas Giolito - Bos Round 2: 2B Romy Gonzalez - Bos |
Round 1: 1B Eric Wagaman - Mia |
| 1st Team | 2nd Team |
| Pre-Season | |
| Basket Case | High Cheese |
|
1B
Kyle Manzardo
Cle |
Round 8, 3rd Pick (SP Zach Eflin Bal) |
| Pre-Season | |
| Basket Case | Slow - Listen - Flow |
|
2B
Kristian Campbell
Bos Round 19, 2nd Pick (3B Miguel Vargas ChA) |
Round 7, 6th Pick (RP Alexis Diaz Cin) |