| Week | Add | Drop |
| Pre-Season |
Round A: 1B Daric Barton - Oak Round C: SP C.J. Wilson - Tex |
Round A: RP Brian Fuentes - LAA Round C: SP Kyle Lohse - StL |
| Week 1 |
Round 1: OF Ryan Church - NYN |
Round 1: 2B Mark DeRosa - Cle |
| Week 2 |
Round 2: SP Jarrod Washburn - Sea | |
| Week 3 |
Round 1: 1B John Bowker - SF | |
| Week 4 |
Round 1: OF Brian S. Giles - SD |
Round 1: 1B John Bowker - SF |
| Week 5 |
Round 1: C Jeff Mathis - LAA Round 2: SP Bronson Arroyo - Cin |
Round 1: C Yorvit Torrealba - Col Round 2: 1B Adam LaRoche - Pit Round 2: SP Gil Meche - KC |
| Week 6 |
Round 1: SP Bartolo Colon - ChA Round 2: SP Gil Meche - KC |
Round 1: SP Bronson Arroyo - Cin |
| Week 7 |
Round 1: SP Aaron Laffey - Cle |
Round 1: 3B Josh Fields - ChA Round 2: SP Gil Meche - KC |
| Week 8 |
Round 1: SP Bronson Arroyo - Cin Round 2: OF Chase Headley - SD |
Round 2: SP Jarrod Washburn - Sea |
| Week 9 |
Round 1: OF David DeJesus - KC Round 2: 1B Adam LaRoche - Pit |
Round 1: SP Mark Buehrle - ChA Round 2: SP Brandon Backe - Hou |
| Week 10 |
Round 1: SP Doug Davis - Ari Round 2: C Jesus Flores - Was |
Round 1: SP Bronson Arroyo - Cin Round 2: C Jeff Mathis - LAA |
| Week 11 |
Round 1: C Kurt Suzuki - Oak Round 2: OF Luke Scott - Bal |
Round 1: OF Chase Headley - SD Round 2: SP Doug Davis - Ari |
| Week 12 |
Round 1: SP Kyle Kendrick - Phi Round 2: SP C.J. Wilson - Tex |
Round 1: SP Bartolo Colon - ChA Round 2: OF Luke Scott - Bal |
| Week 13 |
Round 1: SP Gil Meche - KC Round 2: SP Chris Young - SD |
Round 1: 1B Adam LaRoche - Pit Round 2: RP Jason Isringhausen - StL |
| Week 14 |
Round 1: SS Yuniesky Betancourt - Sea Round 2: 1B Kevin Millar - Bal |
Round 1: SS Jason Bartlett - TB Round 2: OF Eric Byrnes - Ari |
| Week 15 |
Round 1: 2B Jeff Kent - LAD Round 2: OF Matt Joyce - Det |
Round 1: SP Chris Young - SD Round 2: 2B Freddy Sanchez - Pit |
| Week 17 |
Round 2: C Gerald Laird - Tex |
Round 2: C Kurt Suzuki - Oak |
| Week 18 |
Round 1: SP Chris Young - SD |
Round 1: SP Aaron Laffey - Cle |
| Week 19 |
Round 1: RP J.J. Putz - Sea Round 2: 3B Ty Wigginton - Hou |
Round 1: 3B Pedro Feliz - Phi Round 2: SP C.J. Wilson - Tex |
| Week 21 |
Round 1: SP Dave Bush - Mil |
Round 1: SP Tim Wakefield - Bos |
| 1st Team | 2nd Team | Votes |