| Week | Add | Drop |
| Pre-Season |
Round 1: SP Nestor Cortes Jr. - Mil Round A: 2B Luisangel Acuna - NYN | |
| Week 1 |
Round 1: 2B Wilmer Flores - SF Round 2: OF Brandon Marsh - Phi Round 3: SS Kyren Paris - LAA |
Round 2: 1B Ty France - Min Round 3: OF Jhonkensy Noel - Cle |
| Week 2 |
Round 1: RP AJ Puk - Ari Round 2: OF Trent Grisham - NYA Round 3: 3B Jace Jung - Det |
Round 1: 3B Curtis Mead - TB Round 2: OF Taylor Ward - LAA |
| Week 3 |
Round 1: OF Mike Yastrzemski - SF Round 2: RP Emilio Pagan - Cin Round 3: RP AJ Puk - Ari |
Round 1: OF Brandon Marsh - Phi Round 2: RP AJ Puk - Ari |
| Week 4 |
Round 1: SP Zach Eflin - Bal Round 3: SP Hunter Dobbins - Bos |
Round 1: SP Trevor Williams - Was Round 3: RP AJ Puk - Ari |
| Week 5 |
Round 2: C Austin Wynns - Cin Round 3: 2B Hyeseong Kim - LAD |
Round 2: C Ryan Jeffers - Min Round 3: OF Michael Conforto - LAD |
| Week 6 |
Round 1: 1B Colt Keith - Det Round 2: SP Andrew Heaney - Pit |
Round 1: 1B Jake Burger - Tex Round 2: RP Justin Martinez - Ari |
| 1st Team | 2nd Team |