| Week | Add | Drop |
| Pre-Season |
Round 1: RP Kevin Ginkel - Ari Round A: SP Yoshinobu Yamamoto - LAD |
Round 1: SS Wander Franco - TB Round A: 3B Jose Miranda - Min |
| Week 1 |
Round 1: 1B Jared Walsh - ChA |
Round 1: 1B Bobby Dalbec - Bos |
| Week 2 |
Round 1: SP Cody Bradford - Tex Round 2: RP James McArthur - KC |
Round 2: SS Trevor Story - Bos |
| Week 3 |
Round 1: OF Edward Olivares - Pit Round 2: SP Edward Cabrera - Mia |
Round 1: SP AJ Puk - Mia |
| Week 4 |
Round 1: SS Gabriel Arias - Cle Round 2: 1B Ryan O'Hearn - Bal |
Round 1: OF Matt Wallner - Min Round 2: 1B Jared Walsh - ChA |
| Week 5 |
Round 1: OF Jake Fraley - Cin Round 2: C Connor Wong - Bos |
Round 1: RP Kevin Ginkel - Ari Round 2: OF Joey Gallo - Was |
| Week 6 |
Round 1: OF Richie Palacios - TB Round 2: SP Hayden Wesneski - ChN |
Round 1: OF Edward Olivares - Pit Round 2: SS Wander Franco - TB |
| 1st Team | 2nd Team |
| Pre-Season | |
| Ambulance Chasers | The Plantation |
|
Round 13, 1st Pick (SS Orlando Arcia Atl) Round 17, 1st Pick (1B Carlos Santana Min) |
Round 4, 4th Pick (2B Jorge Polanco Sea) Round 5, 4th Pick (SP Triston McKenzie Cle) Round 8, 4th Pick (SP Bryan Woo Sea) |
| Pre-Season | |
| Ambulance Chasers | Akron RubberDucks |
|
SP
Cole Ragans
KC |
Round 1, 5th Pick (3B Jake Burger Mia) Round 3, 5th Pick (SP Justin Verlander Hou) Round 5, 5th Pick (SS Trevor Story Bos) |
| Pre-Season | |
| Ambulance Chasers | Salt Lake Bees |
|
Round 7, 1st Pick (OF Colton Cowser Bal) Round 3, 5th Pick (SP Justin Verlander Hou) |
1B
Spencer Torkelson
Det |