| Week | Add | Drop |
| Pre-Season |
Round 1: SP Mike Lorenzen - KC Round 2: 2B Willi Castro - Min Round 3: 3B Josh Smith - Tex Round A: SP Kodai Senga - NYN Round C: SP Clarke Schmidt - NYA | |
| Week 2 |
Round 3: SP Kyle Hendricks - LAA | |
| Week 3 |
Round 1: SP Antonio Senzatela - Col Round 2: 2B Michael Massey - KC Round 3: SS Jose Caballero - TB |
Round 3: OF MJ Melendez - KC |
| Week 4 |
Round 1: OF Myles Straw - Tor |
Round 1: SP Marcus Stroman - NYA |
| Week 5 |
Round 1: OF Mickey Moniak - Col Round 2: 2B Enmanuel Valdez - Pit Round 3: SP Michael Wacha - KC |
Round 1: 2B Willi Castro - Min Round 2: 2B Michael Massey - KC Round 2: SP Antonio Senzatela - Col Round 3: OF Mickey Moniak - Col |
| Week 6 |
Round 1: SP Tony Gonsolin - LAD |
Round 1: SP Kyle Hendricks - LAA |
| 1st Team | 2nd Team |
| Pre-Season | |
| The Plantation | STDS |
|
Round 2, 5th Pick (1B Christian Encarnacion-Strand Cin) Round 7, 5th Pick (2B Jake Cronenworth SD) |
SP
Pablo Lopez
Min OF Adolis Garcia Tex Round 17, 3rd Pick (SP Marcus Stroman NYA) |