| Week | Add | Drop |
| Week 1 |
Round 1: OF Jay Payton - SD | |
| Week 2 |
Round 1: 2B Jose Offerman - Min | |
| Week 4 |
Round 1: OF Eric Byrnes - Oak |
Round 1: DH Ellis Burks - Bos |
| Week 9 |
Round 1: 3B Kevin Youkilis - Bos |
Round 1: 2B Jose Offerman - Min |
| Week 12 |
Round 1: OF Darin Erstad - Ana | |
| Week 19 |
Round 1: 1B J.T. Snow - SF Round 2: 1B Kevin Millar - Bos |
Round 1: OF Jay Payton - SD Round 2: OF Bobby Kielty - Oak |
| Week 21 |
Round 1: SS Bill Hall - Mil Round 2: 2B Mark Bellhorn - Bos Round 2: 2B Mark Bellhorn - Bos |
Round 1: SP Ryan Wagner - Cin Round 2: SP Jeremy Bonderman - Det |
| 1st Team | 2nd Team | Votes |