| Week | Add | Drop |
| Pre-Season |
Round 1: 3B Miguel Vargas - ChA Round 2: C Carson Kelly - ChN Round A: SP Eury Perez - Mia Round C: SP Andrew Painter - Phi |
Round A: SS Geraldo Perdomo - Ari |
| Week 1 |
Round 1: SS Brayan Rocchio - Cle Round 2: SP Brayan Bello - Bos Round 3: 2B Otto Lopez - Mia |
Round 1: SS Paul DeJong - Was Round 2: 3B Ke'Bryan Hayes - Pit |
| Week 2 |
Round 1: SS Kyren Paris - LAA Round 2: 1B Andrew Vaughn - ChA Round 3: SP Andrew Heaney - Pit |
Round 1: SS Brayan Rocchio - Cle Round 2: OF Ceddanne Rafaela - Bos Round 3: SP Andrew Painter - Phi |
| Week 3 |
Round 1: SP Shane Smith - ChA Round 2: SP Andrew Abbott - Cin Round 3: OF Alex Call - Was |
Round 1: SP Andrew Heaney - Pit Round 2: 1B Andrew Vaughn - ChA Round 3: 3B Miguel Vargas - ChA |
| Week 4 |
Round 1: 2B Luke Keaschall - Min Round 2: 3B Dylan Moore - Sea Round 3: C Agustin Ramirez - Mia |
Round 1: SP Shane Smith - ChA Round 2: OF Max Kepler - Phi Round 3: SP Ronel Blanco - Hou |
| Week 5 |
Round 1: OF Jordan Beck - Col Round 2: SP Andrew Painter - Phi Round 3: 1B Ryan O'Hearn - Bal |
Round 1: OF Alex Call - Was Round 2: 2B Luis Garcia - Was Round 3: 1B Ryan Mountcastle - Bal |
| Week 6 |
Round 1: SS Javier Baez - Det Round 2: 2B Romy Gonzalez - Bos |
| 1st Team | 2nd Team |
| Pre-Season | |
| Fightin Phils | Salt Lake Bees |
|
C
Will Smith
LAD |
Round 3, 6th Pick (OF Pete Crow-Armstrong ChN) |
| Pre-Season | |
| Fightin Phils | Bad Reputation |
|
Round 10, 11th Pick (SP Jameson Taillon ChN) |
Round 15, 4th Pick (RP Aroldis Chapman Bos) Round 16, 4th Pick (3B Ke'Bryan Hayes Pit) Round 18, 4th Pick (SS Paul DeJong Was) |
| Week 5 | |
| Fightin Phils | Salt Lake Bees |
|
3B
Alec Bohm
Phi C Samuel Basallo Bal C Agustin Ramirez Mia 2B Luke Keaschall Min |
3B
Matt Chapman
SF C Will Smith LAD OF Pavin Smith Ari |