| Week | Add | Drop |
| Pre-Season |
Round 2: 1B Willy Aybar - TB Round A: SP Franklin Morales - Col |
Round A: 1B Rich Aurilia - SF |
| Week 1 |
Round 1: SP Brad Thompson - StL Round 2: 2B Jose Lopez - Sea |
Round 2: OF Elijah Dukes - Was |
| Week 2 |
Round 1: 1B Aubrey Huff - Bal Round 2: OF Luke Scott - Bal |
Round 1: OF Brandon Moss - Pit Round 2: 1B Rich Aurilia - SF |
| Week 3 |
Round 1: SP Scott Olsen - Fla Round 2: SP Armando Galarraga - Det |
Round 1: SP Brad Thompson - StL Round 2: OF Franklin Gutierrez - Cle |
| Week 4 |
Round 1: SP Nick Blackburn - Min |
Round 1: 1B Willy Aybar - TB |
| Week 5 |
Round 1: SP Luke Hochevar - KC Round 2: OF Fred Lewis - SF |
Round 1: OF Luke Scott - Bal Round 2: SP Ian Kennedy - NYA |
| Week 6 |
Round 1: 2B Blake Dewitt - LAD Round 2: SP Aaron Laffey - Cle |
Round 1: C J.R. Towles - Hou Round 2: SP Armando Galarraga - Det |
| Week 7 |
Round 1: OF Matt Joyce - Det Round 2: SP Garrett Olson - Bal |
Round 1: SP Curt Schilling - Bos Round 2: RP Jason Isringhausen - StL |
| Week 8 |
Round 1: RP Justin Masterson - Bos Round 2: C Miguel Olivo - KC |
Round 1: SP Nick Blackburn - Min Round 2: OF Fred Lewis - SF |
| Week 9 |
Round 2: SP Daniel Wheeler - TB |
Round 2: OF Matt Joyce - Det |
| Week 10 |
Round 1: SS Alexei Ramirez - ChA |
Round 1: SP Luke Hochevar - KC Round 2: SP Daniel Wheeler - TB |
| Week 11 |
Round 1: SP Ryan Tucker - Fla |
Round 1: RP Dana Eveland - Oak |
| Week 12 |
Round 2: 2B Jeff Baker - Col |
Round 2: SP Ryan Tucker - Fla |
| Week 13 |
Round 2: SP Ricky Nolasco - Fla |
Round 2: SP Garrett Olson - Sea |
| Week 14 |
Round 1: SP Joel Zumaya - Det Round 2: SP Edwin Jackson - TB |
Round 1: 2B Felipe Lopez - Was Round 2: 2B Blake Dewitt - LAD |
| Week 15 |
Round 1: OF Matt Joyce - Det |
Round 1: SP Aaron Laffey - Cle |
| 1st Team | 2nd Team | Votes |
| Pre-Season | ||
| STDS | Fightin Phils | Decision |
|
1B
Carlos Pena
TB |
OF
Bobby Abreu
NYA |
Approved 24-0. See Breakdown |