| Week | Add | Drop |
| Pre-Season |
Round 2: OF Hunter Goodman - Col Round A: 2B Hyeseong Kim - LAD |
Round 2: SP Miles Mikolas - StL |
| Week 1 |
Round 1: OF Sal Frelick - Mil Round 2: OF Victor Scott - StL Round 3: 3B Yoan Moncada - LAA | |
| Week 2 |
Round 1: SS Kyren Paris - LAA Round 2: OF Jonny DeLuca - TB |
Round 1: OF Jo Adell - LAA Round 2: SS Paul DeJong - Was |
| Week 3 |
Round 1: 3B Chase Meidroth - ChA Round 2: SS Max Muncy - Oak |
Round 1: 3B Yoan Moncada - LAA Round 2: OF Joc Pederson - Tex |
| Week 4 |
Round 1: SS Gabriel Arias - Cle |
Round 1: SS Max Muncy - Oak |
| Week 5 |
Round 1: OF Trent Grisham - NYA |
Round 1: 3B Chase Meidroth - ChA |
| Week 6 |
Round 1: 3B Joey Ortiz - Mil |
Round 1: OF Jonny DeLuca - TB |
| 1st Team | 2nd Team |
| Pre-Season | |
| South Bend Silver Hawks | S&M |
|
Round 4, 3rd Pick (RP Robert Suarez SD) |
SP
Tyler Glasnow
LAD |
| Pre-Season | |
| South Bend Silver Hawks | S&M |
|
Round 3, 3rd Pick (OF Pete Crow-Armstrong ChN) |
OF
Luis Robert Jr.
ChA |
| Pre-Season | |
| South Bend Silver Hawks | S&M |
|
3B
Matt Shaw
ChN |
RP
Josh Hader
Hou |