| Week | Add | Drop |
| Pre-Season |
Round 1: RP Will Smith - KC Round 2: OF Alex Verdugo - NYA | |
| Week 1 |
Round 1: OF Steven Kwan - Cle Round 2: OF Adam Duvall - Atl | |
| Week 3 |
Round 1: RP Kyle Finnegan - Was Round 2: 3B Jared Triolo - Pit | |
| Week 4 |
Round 1: SP Edward Cabrera - Mia | |
| Week 5 |
Round 1: 1B Ryan O'Hearn - Bal Round 2: SP Bailey Falter - Pit |
Round 2: RP Will Smith - KC Round 2: OF Adam Duvall - Atl |
| Week 6 |
Round 1: 3B Patrick Wisdom - ChN Round 2: 3B Nick Senzel - Was |
| 1st Team | 2nd Team |
| Pre-Season | |
| St. Paul Gophers | Memphis Red Sox |
|
OF
Jorge Soler
SF |
Round 7, 4th Pick (OF Chas McCormick Hou) |
| Pre-Season | |
| St. Paul Gophers | Putters Revenge |
|
Round 2, 9th Pick (C J.T. Realmuto Phi) Round 4, 9th Pick (SP Joe Ryan Min) |
C
Yan Gomes
ChN |
| Pre-Season | |
| St. Paul Gophers | Romans |
|
Round 3, 9th Pick (RP Andres Munoz Sea) Round 6, 9th Pick (OF Jack Suwinski Pit) Round 8, 9th Pick (SP AJ Puk Mia) |
SP
Cole Ragans
KC |