| Week | Add | Drop |
| Pre-Season |
Round 2: 2B Felipe Lopez - Was Round A: C Geovany Soto - ChN |
Round A: SP Orlando Hernandez - NYN |
| Week 1 |
Round 1: SP Livan Hernandez - Col | |
| Week 2 |
Round 1: OF Angel Pagan - NYN |
Round 1: OF Brad Wilkerson - Bos |
| Week 3 |
Round 1: OF Skip Schumaker - StL | |
| Week 4 |
Round 1: OF Michael Cuddyer - Min Round 2: SP Shawn Chacon - Pit |
Round 2: SP Kyle Kendrick - Phi |
| Week 5 |
Round 1: OF Wladimir Balentien - Sea Round 2: SP Homer Bailey - Cin |
Round 1: OF Angel Pagan - NYN Round 2: OF Jose Guillen - KC Round 2: 2B Felipe Lopez - Was Round 2: SP Scott Olsen - Was |
| Week 6 |
Round 1: SP Mike Mussina - NYA Round 2: 3B Brandon Wood - LAA |
Round 1: OF Skip Schumaker - StL Round 2: SP Jeremy Guthrie - Bal |
| Week 7 |
Round 1: C Kenji Johjima - Sea Round 2: SP Derek Lowe - LAD |
Round 1: 3B Brandon Wood - LAA Round 2: SP Homer Bailey - Cin |
| Week 8 |
Round 1: OF Jose Guillen - KC Round 2: 3B Bill Hall - Mil |
Round 1: SP Shawn Chacon - Pit Round 2: OF Michael Cuddyer - Min |
| Week 9 |
Round 1: OF Lastings Milledge - Was |
Round 1: C Kenji Johjima - Sea |
| Week 10 |
Round 1: OF Mark Teahen - KC Round 2: OF Jose Guillen - KC |
Round 1: OF Jose Guillen - KC Round 2: OF Lastings Milledge - Was |
| Week 11 |
Round 1: SP Jonathan Sanchez - SF Round 2: OF Lastings Milledge - Was |
Round 1: SP Jake Westbrook - Cle Round 2: OF Wladimir Balentien - Sea |
| Week 12 |
Round 1: OF Marcus Thames - Det Round 2: 3B Jeff Keppinger - Cin |
Round 1: SP Livan Hernandez - Col Round 2: SP Joe Blanton - Phi |
| Week 13 |
Round 1: 3B Brian Buscher - Min Round 2: 3B Scott Rolen - Tor |
Round 1: 3B Bill Hall - Mil Round 2: 1B Nick Johnson - Was |
| Week 14 |
Round 1: SP Kyle Kendrick - Phi Round 2: SP Bronson Arroyo - Cin |
Round 1: 3B Jeff Keppinger - Cin Round 2: OF Lastings Milledge - Was |
| Week 15 |
Round 1: 3B Bill Hall - Mil |
Round 1: 3B Brian Buscher - Min |
| Week 17 |
Round 2: SP Josh Johnson - Fla |
Round 2: SP Jonathan Sanchez - SF |
| Week 18 |
Round 1: SP Anibal Sanchez - Fla Round 2: C Jeff Mathis - LAA |
Round 1: OF Jose Guillen - KC Round 2: OF Mark Teahen - KC |
| Week 19 |
Round 1: OF Lastings Milledge - Was |
Round 1: SP Tim Hudson - Atl |
| Week 21 |
Round 1: 2B Asdrubal Cabrera - Cle |
Round 1: C Jeff Mathis - LAA |
| 1st Team | 2nd Team | Votes |
| Week 8 | ||
| Romans | No Clue 2 | Decision |
|
1B
Richie Sexson
Sea |
3B
Mark Reynolds
Ari |
Approved 18-0. See Breakdown |