| Rank | Player | Position | Proteam | Passing Yards |
| 1. | Joe Burrow | QB | Cin | 4918 |
| 2. | Jared Goff | QB | Det | 4629 |
| 3. | Baker Mayfield | QB | TB | 4501 |
| 4. | Geno Smith | QB | Sea | 4321 |
| 5. | Sam Darnold | QB | Min | 4319 |
| 6. | Lamar Jackson | QB | Bal | 4172 |
| 7. | Patrick Mahomes | QB | KC | 3928 |
| 8. | Aaron Rodgers | QB | NYJ | 3897 |
| 9. | Justin Herbert | QB | LAC | 3870 |
| 10. | Brock Purdy | QB | SF | 3864 |
| 11. | Kyler Murray | QB | Ari | 3851 |
| 12. | Bo Nix | QB | Den | 3775 |
| 13. | Matthew Stafford | QB | LAR | 3762 |
| 14. | Josh Allen | QB | Buf | 3731 |
| 15. | C.J. Stroud | QB | Hou | 3727 |
| 16. | Jayden Daniels | QB | Was | 3567 |
| 17. | Caleb Williams | QB | Chi | 3541 |
| 18. | Kirk Cousins | QB | Atl | 3508 |
| 19. | Jordan Love | QB | GB | 3389 |
| 20. | Jalen Hurts | QB | Phi | 2903 |
| 21. | Tua Tagovailoa | QB | Mia | 2867 |
| 22. | Russell Wilson | QB | Pit | 2482 |
| 23. | Bryce Young | QB | Car | 2404 |
| 24. | Drake Maye | QB | NE | 2275 |
| 25. | Derek Carr | QB | NO | 2145 |
| 26. | Jameis Winston | QB | Cle | 2121 |
| 27. | Will Levis | QB | Ten | 2089 |
| 28. | Daniel Jones | QB | NYG | 2070 |
| 29. | Trevor Lawrence | QB | Jac | 2045 |
| 30. | Gardner Minshew | QB | LV | 2013 |
| 31. | Dak Prescott | QB | Dal | 1978 |
| 32. | Cooper Rush | QB | Dal | 1844 |
| 33. | Anthony Richardson | QB | Ind | 1814 |
| 34. | Joe Flacco | QB | Ind | 1761 |
| 35. | Mac Jones | QB | Jac | 1672 |
| 36. | Aidan O'Connell | QB | LV | 1612 |
| 37. | Mason Rudolph | QB | Ten | 1530 |
| 38. | Spencer Rattler | QB | NO | 1317 |
| 39. | Deshaun Watson | QB | Cle | 1148 |
| 40. | Justin Fields | QB | Pit | 1102 |
| 41. | Drew Lock | QB | NYG | 1071 |
| 42. | Andy Dalton | QB | Car | 989 |
| 43. | Tyler Huntley | QB | Mia | 829 |
| 44. | Jacoby Brissett | QB | NE | 826 |
| 45. | Michael Penix Jr. | QB | Atl | 775 |
| 46. | Malik Willis | QB | GB | 550 |
| 47. | Desmond Ridder | QB | Ari | 458 |
| 48. | Dorian Thompson-Robinson | QB | Cle | 440 |
| 49. | Marcus Mariota | QB | Was | 364 |
| 50. | Joshua Dobbs | QB | SF | 361 |