*=Offensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 59.00 | Week 09, 2013 * | Phi | @Oak@Oak | 406 Pass, 14 Rush, 7 TD |
| 2. | 39.94 | Week 16, 2018 | Phi | HouHou | 471 Pass, 1 Rush, 4 TD, 1 Int, 1 Fumb |
| 3. | 39.00 | Week 15, 2013 | Phi | @Min@Min | 428 Pass, 41 Rush, 3 TD, 1 Int, 1 2-Pt |
| 4. | 35.00 | Week 06, 2013 | Phi | @TB@TB | 296 Pass, 2 Rush, 4 TD |
| 4. | 35.00 | Week 14, 2012 | Phi | @TB@TB | 381 Pass, 27 Rush, 3 TD |
| 6. | 33.00 | Week 15, 2017 | Phi | @NYG@NYG | 237 Pass, 4 TD |
| 7. | 32.00 | Week 03, 2014 | Phi | WasWas | 325 Pass, 12 Rush, 3 TD |
| 8. | 29.00 | Week 13, 2013 | Phi | AriAri | 237 Pass, 22 Rush, 3 TD |
| 8. | 29.00 | Week 10, 2013 | Phi | @GB@GB | 228 Pass, 38 Rush, 3 TD, 1 Fumb |
| 10. | 25.56 | Week 09, 2020 | Chi | @TEN@TEN | 334 Pass, 2 Rush, 2 TD |
| 11. | 25.00 | Week 08, 2014 | Phi | @Ari@Ari | 411 Pass, 14 Rush, 2 TD, 2 Int |
| 12. | 24.00 | Week 04, 2015 | StL | @Ari@Ari | 171 Pass, - 1 Rush, 3 TD |
| 13. | 23.22 | Week 03, 2020 | Chi | @Atl@Atl | 188 Pass, - 3 Rush, 3 TD, 1 Int |
| 14. | 22.84 | Week 11, 2019 | Jac | @Ind@Ind | 296 Pass, 5 Receiving, 1 Rec, 2 TD, 1 Int |
| 15. | 22.00 | Week 01, 2015 | StL | SeaSea | 297 Pass, 11 Rush, 2 TD, 2 Fumb |
| 15. | 22.00 | Week 16, 2013 | Phi | ChiChi | 230 Pass, 17 Rush, 2 TD |
| 17. | 21.00 | Week 17, 2013 | Phi | @Dal@Dal | 263 Pass, - 5 Rush, 2 TD, 1 Fumb |
| 17. | 21.00 | Week 14, 2013 | Phi | DetDet | 179 Pass, 23 Rush, 2 TD, 1 Int, 1 2-Pt |
| 17. | 21.00 | Week 11, 2013 | Phi | WasWas | 298 Pass, 47 Rush, 1 TD |
| 20. | 20.88 | Week 08, 2020 | Chi | NONO | 272 Pass, 2 TD, 1 Int |
| 21. | 20.00 | Week 08, 2016 | KC | @Ind@Ind | 223 Pass, - 1 Rush, 2 TD |
| 21. | 20.00 | Week 01, 2014 | Phi | JACJAC | 322 Pass, 2 TD, 1 Int, 2 Fumb |
| 23. | 19.24 | Week 17, 2018 | Phi | @Was@Was | 221 Pass, 4 Rush, 2 TD, 1 Int |
| 24. | 19.00 | Week 02, 2014 | Phi | @Ind@Ind | 331 Pass, 22 Rush, 1 TD, 1 Int |
| 24. | 19.00 | Week 05, 2013 | Phi | @NYG@NYG | 197 Pass, 1 Rush, 2 TD |
| 26. | 18.80 | Week 16, 2021 | Chi | @SEA@SEA | 250 Pass, 8 Rush, 1 TD, 1 2-Pt |
| 27. | 18.66 | Week 02, 2018 | Phi | @TB@TB | 334 Pass, 8 Rush, - 5 Receiving, 1 TD, 1 Fumb |
| 28. | 18.32 | Week 06, 2020 | Chi | @CAR@CAR | 198 Pass, 4 Rush, 2 TD, 1 Int |
| 29. | 18.00 | Week 05, 2014 | Phi | StLStL | 207 Pass, 13 Rush, 2 TD, 1 Int, 1 Fumb |
| 30. | 17.00 | Week 06, 2014 | Phi | NYGNYG | 248 Pass, 5 Rush, 2 TD, 2 Int |
| 30. | 17.00 | Week 16, 2012 | Phi | WasWas | 345 Pass, 10 Rush, 1 TD, 1 Int, 1 Fumb |
| 32. | 16.00 | Week 13, 2012 | Phi | @Dal@Dal | 251 Pass, 1 TD |
| 33. | 14.88 | Week 12, 2019 | Jac | @Ten@Ten | 272 Pass, 20 Rush, 1 2-Pt |
| 34. | 13.86 | Week 04, 2020 | Chi | INDIND | 249 Pass, - 1 Rush, 1 TD, 1 Int |
| 35. | 13.62 | Week 05, 2020 | Chi | TBTB | 243 Pass, - 1 Rush, 1 TD, 1 Int |
| 36. | 13.00 | Week 09, 2016 | KC | JacJac | 187 Pass, - 3 Rush, 1 TD |
| 36. | 13.00 | Week 08, 2015 | StL | SFSF | 191 Pass, - 3 Rush, 1 TD |
| 38. | 12.00 | Week 02, 2015 | StL | @Was@Was | 150 Pass, 1 Rush, 1 TD |
| 39. | 11.00 | Week 10, 2012 | Phi | DalDal | 219 Pass, 1 TD, 1 Int, 1 Fumb |
| 40. | 10.00 | Week 16, 2017 | Phi | OakOak | 163 Pass, 1 TD, 1 Int |
| 40. | 10.00 | Week 15, 2012 | Phi | CinCin | 182 Pass, 5 Rush, 1 TD, 1 Int, 1 Fumb |
| 42. | 9.30 | Week 15, 2018 | Phi | @LAR@LAR | 270 Pass, 5 Rush, 1 Int |
| 43. | 9.00 | Week 01, 2019 | Jac | KCKC | 75 Pass, 1 TD |
| 44. | 8.00 | Week 09, 2014 | Phi | @Hou@Hou | 124 Pass, 1 Rush, 1 TD, 1 Int |
| 45. | 7.00 | Week 04, 2013 | Phi | @Den@Den | 49 Pass, 1 TD |
| 46. | 6.44 | Week 07, 2020 | Chi | @LAR@LAR | 261 Pass, 2 Int |
| 47. | 6.00 | Week 10, 2015 | StL | ChiChi | 200 Pass, 1 Int |
| 47. | 6.00 | Week 09, 2015 | StL | @Min@Min | 168 Pass, 2 Rush |
| 47. | 6.00 | Week 07, 2015 | StL | CleCle | 163 Pass, - 2 Rush |
| 47. | 6.00 | Week 03, 2015 | StL | PitPit | 197 Pass, 10 Rush, 1 Int |