*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 22.00 | Week 17, 2018 | Buf | MiaMia | 11 Tackles, 1 Assist, 1.0 Sack, 1 Int, 1 PD |
| 2. | 21.00 | Week 15, 2023 | Chi | @Cle@Cle | 5 Tackles, 4 Assists, 1 Int, 1 TD, 1 PD |
| 3. | 17.00 | Week 08, 2022 | Buf | GBGB | 13 Tackles, 3 Assists, 1 PD |
| 4. | 16.00 | Week 02, 2023 | Chi | @TB@TB | 8 Tackles, 8 Assists |
| 4. | 16.00 | Week 09, 2020 | Buf | SEASEA | 8 Tackles, 3 Assists, 1.0 Sack, 1 PD |
| 4. | 16.00 | Week 01, 2018 | Buf | BalBal | 3 Tackles, 4 Assists, 1.0 Sack, 1 FF, 2 PD |
| 7. | 15.00 | Week 02, 2024 | Chi | @Hou@Hou | 8 Tack, 3 Ass, 1.00 Sack |
| 7. | 15.00 | Week 07, 2023 | Chi | LVLV | 6 Tackles, 2 Assists, 1 Int, 2 PD |
| 7. | 15.00 | Week 18, 2022 | Buf | NENE | 6 Tackles, 1 Assist, 1 Int, 3 PD |
| 7. | 15.00 | Week 11, 2019 | Buf | @Mia@Mia | 5 Tackles, 7 Assists, 0.5 Sack, 1 PD |
| 11. | 14.00 | Week 11, 2023 | Chi | @Det@Det | 4 Tackles, 4 Assists, 1 Int, 1 PD |
| 11. | 14.00 | Week 14, 2019 | Buf | BalBal | 6 Tackles, 2 Assists, 1 Int, 1 PD |
| 11. | 14.00 | Week 14, 2018 | Buf | NYJNYJ | 5 Tackles, 3 Assists, 1 Int, 1 PD |
| 14. | 13.00 | Week 14, 2023 | Chi | DetDet | 4 Tackles, 3 Assists, 1 Int, 1 PD |
| 14. | 13.00 | Week 14, 2021 | Buf | @TB@TB | 6 Tackles, 6 Assists, 1 PD |
| 14. | 13.00 | Week 17, 2020 | Buf | MIAMIA | 5 Tackles, 4 Assists, 1.0 Sack |
| 17. | 12.00 | Week 03, 2024 | Chi | @Ind@Ind | 3 Tack, 2 Ass, 1 Int, 2 PD |
| 17. | 12.00 | Week 04, 2021 | Buf | HOUHOU | 3 Tackles, 3 Assists, 1 Int, 1 PD |
| 17. | 12.00 | Week 12, 2020 | Buf | LACLAC | 3 Tackles, 8 Assists, 1 PD |
| 17. | 12.00 | Week 06, 2020 | Buf | KCKC | 8 Tackles, 4 Assists |
| 17. | 12.00 | Week 04, 2020 | Buf | @LV@LV | 8 Tackles, 4 Assists |
| 17. | 12.00 | Week 04, 2019 | Buf | NENE | 7 Tackles, 4 Assists, 1 PD |
| 17. | 12.00 | Week 16, 2018 | Buf | @NE@NE | 3 Tackles, 8 Assists, 1 PD |
| 17. | 12.00 | Week 05, 2018 | Buf | TenTen | 4 Tackles, 4 Assists, 1 FF, 1 PD |
| 25. | 11.00 | Week 09, 2022 | Buf | @NYJ@NYJ | 3 Tackles, 8 Assists |
| 25. | 11.00 | Week 10, 2019 | Buf | @Cle@Cle | 2 Tackles, 2 Assists, 1.0 Sack, 1 PD, 1 Safety |
| 25. | 11.00 | Week 03, 2018 | Buf | @Min@Min | 7 Tackles, 3 Assists, 1 PD |
| 28. | 10.00 | Week 18, 2024 | Chi | @GB @GB | 4 Tack, 5 Ass, 1 PD |
| 28. | 10.00 | Week 12, 2024 | Chi | MinMin | 4 Tack, 5 Ass, 1 PD |
| 28. | 10.00 | Week 08, 2024 | Chi | @Was@Was | 4 Tack, 6 Ass |
| 28. | 10.00 | Week 12, 2023 | Chi | @Min@Min | 5 Tackles, 2 Assists, 1 FF |
| 28. | 10.00 | Week 06, 2023 | Chi | MinMin | 2 Tackles, 4 Assists, 1 Fum Rcvy, 1 PD |
| 28. | 10.00 | Week 06, 2022 | Buf | @KC@KC | 5 Tackles, 5 Assists |
| 28. | 10.00 | Week 01, 2022 | Buf | @LAR@LAR | 7 Tackles, 3 Assists |
| 28. | 10.00 | Week 06, 2021 | Buf | @TEN@TEN | 8 Tackles, 2 Assists |
| 28. | 10.00 | Week 10, 2020 | Buf | @ARI@ARI | 7 Tackles, 3 Assists |
| 37. | 9.00 | Week 05, 2024 | Chi | CarCar | 4 Tack, 2 Ass, 1 FF |
| 37. | 9.00 | Week 18, 2023 | Chi | @GB@GB | 7 Tackles, 2 Assists |
| 37. | 9.00 | Week 05, 2023 | Chi | @Was@Was | 2 Tackles, 7 Assists |
| 37. | 9.00 | Week 16, 2022 | Buf | @Chi@Chi | 5 Tackles, 4 Assists |
| 37. | 9.00 | Week 04, 2022 | Buf | @Bal@Bal | 5 Tackles, 4 Assists |
| 37. | 9.00 | Week 05, 2021 | Buf | @KC@KC | 6 Tackles, 3 Assists |
| 37. | 9.00 | Week 05, 2020 | Buf | @TEN@TEN | 4 Tackles, 4 Assists, 1 PD |
| 37. | 9.00 | Week 16, 2019 | Buf | @NE@NE | 5 Tackles, 4 Assists |
| 37. | 9.00 | Week 15, 2019 | Buf | @Pit@Pit | 6 Tackles, 2 Assists, 1 PD |
| 37. | 9.00 | Week 08, 2019 | Buf | PhiPhi | 7 Tackles, 2 Assists |
| 37. | 9.00 | Week 08, 2018 | Buf | NENE | 6 Tackles, 2 Assists, 1 PD |
| 37. | 9.00 | Week 06, 2018 | Buf | @Hou@Hou | 7 Tackles, 2 Assists |
| 49. | 8.00 | Week 14, 2024 | Chi | @SF @SF | 3 Tack, 5 Ass |
| 49. | 8.00 | Week 04, 2023 | Chi | DenDen | 6 Tackles, 2 Assists |