| Acuna Machado - ML6 | Santa’s Stars - ML6 |
| Week 1 | |
|
3B Manny Machado SD SP Daniel Norris F/A SS Orlando Arcia Col |
1B Miguel Sano LAA SS Francisco Lindor NYN SP Luis Severino Oak |
| The trade was approved 9-1. See Breakdown | |
| Brokeback Mountain - EL7 | The Plantation - EL7 |
| Week 3 | |
|
SS Trevor Story Bos SP Kyle Hendricks LAA C Tony Wolters F/A |
SP Max Scherzer Tor |
| The trade was approved 11-1. See Breakdown | |
| Columbus Blue Birds - EL4 | Whiz Kids - EL4 |
| Week 4 | |
|
3B Matt Davidson F/A |
DH Justin Turner ChN 1B Greg Bird F/A SP Jacob deGrom Tex |
| The trade was approved 8-1. See Breakdown | |
| Acuna Machado - ML6 | Santa’s Stars - ML6 |
| Week 4 | |
|
SP Aaron Nola Phi |
RP Tony Watson F/A RP Taijuan Walker Phi |
| The trade was approved 10-0. See Breakdown | |
| Portland Pickles - ML28 | PREPARATION + OPPORTUNITY - ML28 |
| Week 4 | |
|
SP Lance Lynn StL 3B Eugenio Suarez Sea |
SP Sonny Gray Bos |
| The trade was approved 10-1. See Breakdown | |
| Everett AquaSox - ML26 | Page Fence Giants - ML26 |
| Week 5 | |
|
SS Xander Bogaerts SD RP Kendall Graveman Ari |
SP Jose Quintana Mil OF Chris Owings LAD |
| The trade was approved 10-2. See Breakdown | |
| PREPARATION + OPPORTUNITY - ML28 | Portland Pickles - ML28 |
| Week 6 | |
|
SP Lance Lynn StL C Austin Hedges Cle |
SP Zack Wheeler Phi RP Steven Matz Bos SP Blake Snell LAD |
| The trade was approved 11-1. See Breakdown | |
| Banzai - ML5 | Black Sox - ML5 |
| Week 14 | |
|
C Salvador Perez KC |
|
| The trade was approved 11-0. See Breakdown | |