| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Will Smith | C | LAD | 30 | |
| Austin Wells | C | NYA | 25 | |
| Yandy Diaz | 1B | TB | 33 | |
| Josh Naylor | 1B | Ari | 27 | |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Spencer Torkelson | 1B | Det | 25 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| Brandon Lowe | 2B | TB | 30 | |
| Oswaldo Cabrera | SS (3B) | NYA | 26 | |
| Carlos Correa | SS | Min | 30 | |
| Marcelo Mayer | SS | Bos | 22 | |
| Trevor Story | SS | Bos | 32 | |
| Alex Bregman | 3B | Bos | 31 | |
| JJ Bleday | OF | Oak | 27 | |
| Ian Happ | OF | ChN | 30 | |
| Spencer Jones | OF | NYA | 23 | |
| Steven Kwan | OF | Cle | 27 | |
| Jorge Soler | OF | LAA | 32 | |
| Seiya Suzuki | OF | ChN | 30 | |
| Chris Bassitt | SP | Tor | 36 | |
| Brayan Bello | SP | Bos | 25 | |
| Shane Bieber | SP | Cle | 29 | March 27, 2025:15 Day IL |
| Walker Buehler | SP | Bos | 30 | May 02, 2025:15 Day IL-Shoulder |
| Kevin Gausman | SP | Tor | 34 | |
| Mitch Keller | SP | Pit | 29 | |
| Merrill Kelly | SP | Ari | 36 | |
| Kodai Senga | SP | NYN | 32 | |
| Jameson Taillon | SP | ChN | 33 | |
| Logan Webb | SP | SF | 28 | |
| Gavin Williams | SP | Cle | 25 | |
| Edwin Diaz | RP | NYN | 31 | |
| Camilo Doval | RP | SF | 27 | |
| Shelby Miller | RP | Ari | 34 |