| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Agustin Ramirez | C | Mia | 23 | |
| Adley Rutschman | C | Bal | 27 | |
| Austin Wells | C | NYA | 25 | |
| Jac Caglianone | 1B | KC | 22 | |
| Nick Kurtz | 1B | Oak | 22 | |
| Kyle Manzardo | 1B | Cle | 24 | |
| Josh Naylor | 1B | Ari | 27 | |
| Luisangel Acuna | 2B | NYN | 23 | |
| Kristian Campbell | 2B (OF) | Bos | 22 | |
| Jackson Holliday | 2B (SS) | Bal | 21 | |
| Luke Keaschall | 2B | Min | 22 | April 26, 2025:10 Day IL |
| Gunnar Henderson | SS | Bal | 23 | |
| Marcelo Mayer | SS | Bos | 22 | |
| Bobby Witt Jr. | SS | KC | 24 | |
| Cam Smith | 3B (OF) | Hou | 22 | |
| Pete Crow-Armstrong | OF | ChN | 23 | |
| Tommy Edman | OF (2B) | LAD | 29 | |
| Julio Rodriguez | OF | Sea | 24 | |
| Fernando Tatis Jr. | OF | SD | 26 | |
| Shohei Ohtani | DH ,SP | LAD | 30 | |
| Bubba Chandler | SP | Pit | N/A | |
| Garrett Crochet | SP | Bos | 25 | |
| Tony Gonsolin | SP | LAD | 30 | |
| Clay Holmes | SP | NYN | 32 | |
| Jackson Jobe | SP | Det | 22 | |
| Jesus Luzardo | SP | Phi | 27 | |
| Zebby Matthews | SP | Min | N/A | |
| Landen Roupp | SP | SF | N/A | |
| José Alvarado | RP | Phi | 29 | |
| Emmanuel Clase | RP | Cle | 27 | |
| Jeff Hoffman | RP | Tor | 32 | |
| Shelby Miller | RP | Ari | 34 |