| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Samuel Basallo | C | Bal | 20 | |
| Yainer Diaz | C | Hou | 26 | |
| Edgar Quero | C | ChA | 22 | |
| Nick Kurtz | 1B | Oak | 22 | |
| Josh Naylor | 1B | Ari | 27 | |
| Kristian Campbell | 2B (OF) | Bos | 22 | |
| Nico Hoerner | 2B | ChN | 27 | |
| Bo Bichette | SS | Tor | 27 | |
| Jordan Lawlar | SS | Ari | 22 | |
| Marcelo Mayer | SS | Bos | 22 | |
| Zach Neto | SS | LAA | 24 | |
| Trevor Story | SS | Bos | 32 | |
| Ke'Bryan Hayes | 3B | Pit | 28 | |
| Chase Meidroth | 3B (2B,SS) | ChA | N/A | |
| Jose Ramirez | 3B | Cle | 32 | |
| Cam Smith | 3B (OF) | Hou | 22 | |
| Ronald Acuna Jr. | OF | Atl | 27 | March 25, 2025:10 Day IL |
| Roman Anthony | OF | Bos | 20 | |
| Pete Crow-Armstrong | OF | ChN | 23 | |
| Sal Frelick | OF | Mil | 25 | |
| Jackson Merrill | OF | SD | 22 | April 08, 2025:10 Day IL |
| Lars Nootbaar | OF | StL | 27 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Fernando Tatis Jr. | OF | SD | 26 | |
| Jack Flaherty | SP | Det | 29 | |
| Lucas Giolito | SP | Bos | 30 | |
| Andrew Heaney | SP | Pit | 33 | |
| Tyler Mahle | SP | Tex | 30 | |
| Casey Mize | SP | Det | 28 | |
| Cole Ragans | SP | KC | 27 | |
| Edwin Diaz | RP | NYN | 31 | |
| Ryan Helsley | RP | StL | 30 | |
| Mason Miller | RP | Oak | 26 |