| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Victor Caratini | C (C,1B) | Hou | 32 | |
| Ivan Herrera | C | StL | 25 | |
| Adley Rutschman | C | Bal | 27 | August 21, 2025:10 Day IL |
| Michael Busch | 1B | ChN | 27 | |
| Josh Naylor | 1B | Sea | 28 | |
| Nolan Schanuel | 1B | LAA | 23 | August 24, 2025:10 Day IL |
| Nolan Gorman | 2B (1B,3B) | StL | 25 | |
| Zach McKinstry | 2B (SS,3B,OF) | Det | 30 | |
| Gleyber Torres | 2B | Det | 28 | |
| Mookie Betts | SS | LAD | 32 | |
| Francisco Lindor | SS | NYN | 31 | |
| Dansby Swanson | SS | ChN | 31 | |
| Matt Chapman | 3B | SF | 32 | |
| Yoan Moncada | 3B | LAA | 30 | |
| Cody Bellinger | OF (1B) | NYA | 30 | |
| Andrew Benintendi | OF | ChA | 31 | |
| TJ Friedl | OF | Cin | 30 | |
| Adolis Garcia | OF | Tex | 32 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Jesus Sanchez | OF | Hou | 27 | |
| Jose Berrios | SP | Tor | 31 | |
| Shane Bieber | SP | Tor | 30 | |
| Jacob deGrom | SP | Tex | 37 | |
| Bailey Falter | SP | KC | 28 | August 23, 2025:15 Day IL |
| Hunter Greene | SP | Cin | 26 | |
| Shota Imanaga | SP | ChN | 32 | |
| Cristian Javier | SP | Hou | 28 | |
| David Peterson | SP | NYN | 30 | |
| Max Scherzer | SP | Tor | 41 | |
| Pete Fairbanks | RP | TB | 31 | |
| Robert Garcia | RP | Tex | N/A | |
| Andres Munoz | RP | Sea | 26 | |
| Robert Suarez | RP | SD | 34 |