| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Shea Langeliers | C | Oak | 27 | |
| Bo Naylor | C | Cle | 25 | |
| Josh Naylor | 1B | Ari | 27 | |
| Ben Rice | 1B | NYA | 26 | |
| Nolan Gorman | 2B | StL | 24 | |
| Gavin Lux | 2B (OF) | Cin | 27 | |
| Jeff McNeil | 2B | NYN | 33 | |
| Oswaldo Cabrera | SS (3B) | NYA | 26 | |
| Corey Seager | SS | Tex | 31 | |
| Matt Chapman | 3B | SF | 32 | |
| Josh Smith | 3B (SS) | Tex | 27 | |
| Tommy Edman | OF (2B) | LAD | 29 | May 03, 2025:10 Day IL |
| Spencer Jones | OF | NYA | 23 | |
| Aaron Judge | OF | NYA | 33 | |
| Ceddanne Rafaela | OF | Bos | 24 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Jorge Soler | OF | LAA | 32 | |
| Marcell Ozuna | DH | Atl | 34 | |
| Chris Bassitt | SP | Tor | 36 | |
| Shane Bieber | SP | Cle | 29 | March 27, 2025:15 Day IL |
| Erick Fedde | SP | StL | 32 | |
| Jack Flaherty | SP | Det | 29 | |
| Merrill Kelly | SP | Ari | 36 | |
| Nick Lodolo | SP | Cin | 27 | |
| Lance McCullers | SP | Hou | 31 | March 27, 2025:15 Day IL |
| Aaron Nola | SP | Phi | 31 | |
| Reese Olson | SP | Det | 25 | |
| Chris Sale | SP | Atl | 36 | |
| Cristopher Sanchez | SP | Phi | 28 | |
| Felix Bautista | RP | Bal | 29 | |
| Emmanuel Clase | RP | Cle | 27 | |
| Josh Hader | RP | Hou | 31 | |
| Will Vest | RP | Det | 29 |