| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Miguel Amaya | C | ChN | 26 | |
| Colt Keith | 1B (2B) | Det | 23 | |
| Josh Naylor | 1B | Ari | 27 | |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Travis Bazzana | 2B | Cle | 22 | |
| Luis Garcia | 2B | Was | 24 | |
| Nico Hoerner | 2B | ChN | 27 | |
| Trea Turner | SS | Phi | 31 | |
| Bobby Witt Jr. | SS | KC | 24 | |
| Isaac Paredes | 3B | Hou | 26 | |
| Cam Smith | 3B (OF) | Hou | 22 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Jarren Duran | OF | Bos | 28 | |
| Hunter Goodman | OF (C) | Col | 25 | |
| Walker Jenkins | OF | Min | 20 | |
| Jackson Merrill | OF | SD | 22 | April 08, 2025:10 Day IL |
| Julio Rodriguez | OF | Sea | 24 | |
| Jorge Soler | OF | LAA | 32 | |
| Kyle Tucker | OF | ChN | 28 | |
| Alex Verdugo | OF | Atl | 28 | |
| Christian Yelich | OF | Mil | 33 | |
| Luis Castillo | SP | Sea | 32 | |
| Clay Holmes | SP | NYN | 32 | |
| Grant Holmes | SP | Atl | N/A | |
| Michael King | SP | SD | 29 | |
| Sean Manaea | SP | NYN | 33 | March 27, 2025:60 Day IL |
| Dustin May | SP | LAD | 27 | |
| Casey Mize | SP | Det | 28 | |
| David Peterson | SP | NYN | 29 | |
| Grayson Rodriguez | SP | Bal | 25 | March 27, 2025:60 Day IL |
| Spencer Strider | SP | Atl | 26 | April 21, 2025:15 Day IL |
| David Bednar | RP | Pit | 30 | |
| Taijuan Walker | RP (SP) | Phi | 32 |