| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Dillon Dingler | C | Det | N/A | |
| Adley Rutschman | C | Bal | 27 | |
| Joshua Bell | 1B | Was | 32 | |
| Ryan Mountcastle | 1B | Bal | 28 | |
| Christian Walker | 1B | Hou | 34 | |
| Brendan Donovan | 2B (SS,OF) | StL | 28 | |
| Wilmer Flores | 2B | SF | 33 | |
| Ketel Marte | 2B | Ari | 31 | |
| Willy Adames | SS | SF | 29 | |
| Geraldo Perdomo | SS | Ari | 25 | |
| Nolan Arenado | 3B | StL | 34 | |
| Rafael Devers | 3B | Bos | 28 | |
| Max Muncy | 3B | LAD | 34 | |
| Nick Castellanos | OF | Phi | 33 | |
| TJ Friedl | OF | Cin | 29 | |
| Adolis Garcia | OF | Tex | 32 | |
| Lourdes Gurriel | OF | Ari | 31 | |
| Trevor Larnach | OF | Min | 28 | |
| Kyle Stowers | OF | Mia | 27 | |
| Marcell Ozuna | DH | Atl | 34 | |
| Tyler Anderson | SP | LAA | 35 | |
| Osvaldo Bido | SP | Oak | N/A | |
| Tony Gonsolin | SP | LAD | 30 | |
| Jake Irvin | SP | Was | 28 | |
| Merrill Kelly | SP | Ari | 36 | |
| Matthew Liberatore | SP | StL | 25 | |
| Seth Lugo | SP | KC | 35 | |
| Sean Manaea | SP | NYN | 33 | March 27, 2025:60 Day IL |
| Carlos Rodon | SP | NYA | 32 | |
| Brady Singer | SP | Cin | 28 | |
| Blake Snell | SP | LAD | 32 | April 06, 2025:15 Day IL-Ab strain |
| Carlos Estevez | RP | KC | 32 | |
| Kyle Finnegan | RP | Was | 33 |