| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Mitch Garver | C | Min | 29 | |
| Yadier Molina | C | StL | 38 | |
| Brandon Belt | 1B | SF | 32 | |
| Albert Pujols | 1B (DH) | LAA | 40 | |
| Carlos Santana | 1B | Cle | 34 | |
| Brandon Lowe | 2B (OF,DH) | TB | 26 | |
| Jonathan Schoop | 2B | Det | 29 | September 13, 2020:10 Day IL-Sprained right wrist |
| Elvis Andrus | SS | Tex | 32 | September 12, 2020:10 Day IL-Lower back strain |
| Adalberto Mondesà | SS | KC | 25 | |
| Matt Chapman | 3B | Oak | 27 | September 09, 2020:10 Day IL-Strained right hip - out for season |
| Dylan Moore | 3B (1B,2B,SS,OF) | Sea | 28 | September 22, 2020:7 Day IL-Concussion |
| Rio Ruiz | 3B | Bal | 26 | |
| Hunter Dozier | OF (1B) | KC | 29 | |
| JaCoby Jones | OF | Det | 28 | September 02, 2020:10 Day IL-Fractured left hand |
| Andrew McCutchen | OF (DH) | Phi | 34 | |
| Brandon Nimmo | OF | NYN | 27 | |
| Tommy Pham | OF (DH) | SD | 32 | |
| Franmil Reyes | OF (DH) | Cle | 25 | |
| Julio Rodriguez | OF | Sea | 19 | |
| Justin Upton | OF (DH) | LAA | 33 | |
| J.D. Martinez | DH (OF) | Bos | 33 | |
| Pat Corbin | SP | Was | 31 | |
| Zach Davies | SP | SD | 27 | |
| Zac Gallen | SP | Ari | 25 | |
| Tony Gonsolin | SP | LAD | 26 | |
| Steven Matz | SP (RP) | NYN | 28 | |
| David Peterson | SP | NYN | 25 | |
| Michael Pineda | SP | Min | 31 | |
| Chris Sale | SP | Bos | 31 | June 28, 2020:60 Day IL-Left elbow surgery - out for season |
| Mike Soroka | SP | Atl | 23 | August 04, 2020:60 Day IL-Torn right Achilles - out for season |
| Spencer Turnbull | SP | Det | 28 | |
| Zach Wheeler | SP | Phi | 30 | |
| Liam Hendriks | RP | Oak | 31 | |
| Kenley Jansen | RP | LAD | 33 |