| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Samuel Basallo | C | Bal | 20 | |
| William Contreras | C | Mil | 27 | |
| Pedro Pages | C | StL | 26 | |
| Willson Contreras | 1B | StL | 32 | |
| Kyle Manzardo | 1B | Cle | 24 | |
| Josh Naylor | 1B | Ari | 27 | |
| Luke Keaschall | 2B | Min | 22 | April 26, 2025:10 Day IL |
| Marcus Semien | 2B | Tex | 34 | |
| Bryson Stott | 2B | Phi | 27 | |
| CJ Abrams | SS | Was | 24 | |
| Javier Baez | SS (3B,OF) | Det | 32 | |
| Sebastian Walcott | SS | Tex | 19 | |
| Alec Bohm | 3B | Phi | 28 | |
| Caleb Durbin | 3B | Mil | 25 | |
| Wilyer Abreu | OF | Bos | 25 | |
| Jordan Beck | OF | Col | 24 | |
| Cody Bellinger | OF | NYA | 29 | |
| Pete Crow-Armstrong | OF | ChN | 23 | |
| Adolis Garcia | OF | Tex | 32 | |
| Heliot Ramos | OF | SF | 25 | |
| George Springer | OF | Tor | 35 | |
| Shohei Ohtani | DH ,SP | LAD | 30 | |
| Jacob deGrom | SP | Tex | 36 | |
| Lucas Giolito | SP | Bos | 30 | |
| MacKenzie Gore | SP | Was | 26 | |
| Gunnar Hoglund | SP | Oak | 25 | |
| Jackson Jobe | SP | Det | 22 | |
| George Kirby | SP | Sea | 27 | March 27, 2025:15 Day IL |
| Andrew Painter | SP | Phi | N/A | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| Cristopher Sanchez | SP | Phi | 28 | |
| Emmanuel Clase | RP | Cle | 27 | |
| Trevor Megill | RP | Mil | 31 | |
| Mason Miller | RP | Oak | 26 |