| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Logan O'Hoppe | C | LAA | 25 | |
| Keibert Ruiz | C | Was | 26 | |
| Joshua Bell | 1B | Was | 32 | |
| Paul Goldschmidt | 1B | NYA | 37 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| Bo Bichette | SS | Tor | 27 | |
| Josh Jung | 3B | Tex | 27 | |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Luis Urias | 3B (2B) | Oak | 27 | |
| Jordan Westburg | 3B (2B) | Bal | 26 | April 28, 2025:10 Day IL |
| Ronald Acuna Jr. | OF | Atl | 27 | March 25, 2025:10 Day IL |
| Roman Anthony | OF | Bos | 20 | |
| Byron Buxton | OF | Min | 31 | |
| Corbin Carroll | OF | Ari | 24 | |
| Oneil Cruz | OF | Pit | 26 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Parker Meadows | OF | Det | 25 | March 24, 2025:60 Day IL |
| Alex Verdugo | OF | Atl | 28 | |
| Chris Bassitt | SP | Tor | 36 | |
| Taj Bradley | SP | TB | 24 | |
| Dylan Cease | SP | SD | 29 | |
| Zach Eflin | SP | Bal | 31 | April 09, 2025:15 Day IL |
| Erick Fedde | SP | StL | 32 | |
| Aaron Nola | SP | Phi | 31 | |
| Chad Patrick | SP | Mil | N/A | |
| Ryan Pepiot | SP | TB | 27 | |
| Martin Perez | SP | ChA | 34 | April 19, 2025:60 Day IL |
| Brandon Pfaadt | SP | Ari | 26 | |
| Colin Rea | SP (RP) | ChN | 34 | |
| Aroldis Chapman | RP | Bos | 37 | |
| Alexis Diaz | RP | Cin | 28 | |
| Kenley Jansen | RP | LAA | 37 | |
| Emilio Pagan | RP | Cin | 33 |