| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Samuel Basallo | C | Bal | 20 | |
| Cal Raleigh | C | Sea | 28 | |
| Agustin Ramirez | C | Mia | 23 | |
| Bryce Eldridge | 1B | SF | 20 | |
| Ryan Mountcastle | 1B | Bal | 28 | |
| Josh Naylor | 1B | Ari | 27 | |
| Kristian Campbell | 2B (OF) | Bos | 22 | |
| Luis Garcia | 2B | Was | 24 | |
| Mookie Betts | SS | LAD | 32 | |
| Kyren Paris | SS (2B,OF) | LAA | 23 | |
| Matt Chapman | 3B | SF | 32 | |
| Caleb Durbin | 3B | Mil | 25 | |
| Isaac Paredes | 3B | Hou | 26 | |
| Jordan Beck | OF | Col | 24 | |
| Adolis Garcia | OF | Tex | 32 | |
| Bryan Reynolds | OF | Pit | 30 | |
| Kyle Schwarber | OF | Phi | 32 | |
| Kyle Tucker | OF | ChN | 28 | |
| Christian Yelich | OF | Mil | 33 | |
| Chris Bassitt | SP | Tor | 36 | |
| Kris Bubic | SP | KC | 27 | |
| Lucas Giolito | SP | Bos | 30 | |
| MacKenzie Gore | SP | Was | 26 | |
| Gunnar Hoglund | SP | Oak | 25 | |
| Jesus Luzardo | SP | Phi | 27 | |
| Dustin May | SP | LAD | 27 | |
| Andrew Painter | SP | Phi | N/A | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| Framber Valdez | SP | Hou | 31 | |
| David Bednar | RP | Pit | 30 | |
| Aroldis Chapman | RP | Bos | 37 | |
| Emmanuel Clase | RP | Cle | 27 |