| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Joey Bart | C | Pit | 28 | |
| Logan O'Hoppe | C | LAA | 25 | |
| Joshua Bell | 1B | Was | 32 | |
| Matt Olson | 1B | Atl | 31 | |
| Willi Castro | 2B (SS,3B) | Min | 28 | April 24, 2025:10 Day IL |
| Gleyber Torres | 2B | Det | 28 | |
| Francisco Lindor | SS | NYN | 31 | |
| Dansby Swanson | SS | ChN | 31 | |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Eugenio Suarez | 3B | Ari | 33 | |
| Miguel Vargas | 3B | ChA | 25 | |
| Nick Castellanos | OF | Phi | 33 | |
| Ian Happ | OF | ChN | 30 | |
| Brandon Nimmo | OF | NYN | 32 | |
| Bryan Reynolds | OF | Pit | 30 | |
| Victor Scott | OF | StL | 24 | |
| George Springer | OF | Tor | 35 | |
| Chris Bassitt | SP | Tor | 36 | |
| Jose Berrios | SP | Tor | 30 | |
| Dylan Cease | SP | SD | 29 | |
| Aaron Civale | SP | Mil | 29 | March 31, 2025:15 Day IL-Strained left hamstring |
| Erick Fedde | SP | StL | 32 | |
| Andrew Heaney | SP | Pit | 33 | |
| Nick Pivetta | SP | SD | 32 | |
| AJ Smith-Shawver | SP | Atl | 22 | |
| Jameson Taillon | SP | ChN | 33 | |
| Framber Valdez | SP | Hou | 31 | |
| Logan Webb | SP | SF | 28 | |
| Josh Hader | RP | Hou | 31 | |
| Jeff Hoffman | RP | Tor | 32 | |
| Kenley Jansen | RP | LAA | 37 | |
| Emilio Pagan | RP | Cin | 33 | |
| Will Vest | RP | Det | 29 |