| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Robinson Chirinos | C | NYN | 36 | |
| Paul Goldschmidt | 1B (DH) | StL | 33 | |
| Ryan O'Hearn | 1B (DH) | KC | 27 | |
| Jared Walsh | 1B | LAA | 27 | |
| Starlin Castro | 2B | Was | 30 | August 14, 2020:10 Day IL-Fractured right wrist |
| Ketel Marte | 2B (OF) | Ari | 27 | |
| Bo Bichette | SS (DH) | Tor | 22 | |
| Niko Goodrum | SS (2B) | Det | 28 | |
| Asdrubal Cabrera | 3B (1B,DH) | Was | 35 | |
| Jeimer Candelario | 3B (1B) | Det | 27 | September 25, 2020:10 Day IL-Lower back strain |
| Ryan Mountcastle | 3B (1B,OF) | Bal | 23 | |
| Anthony Rendon | 3B | LAA | 30 | |
| Aristides Aquino | OF (DH) | Cin | 26 | |
| Willie Calhoun | OF (DH) | Tex | 26 | |
| Mark Canha | OF (1B,DH) | Oak | 31 | |
| J.D. Davis | OF (3B,DH) | NYN | 27 | |
| Brett Gardner | OF | NYA | 37 | |
| Sam Hilliard | OF | Col | 26 | |
| Justin Upton | OF (DH) | LAA | 33 | |
| J.D. Martinez | DH (OF) | Bos | 33 | |
| Jose Berrios | SP | Min | 26 | |
| Griffin Canning | SP | LAA | 24 | |
| Mike Clevinger | SP | SD | 29 | |
| Pat Corbin | SP | Was | 31 | |
| Brent Honeywell | SP | TB | 25 | |
| Brendan McKay | SP | TB | 24 | |
| Jose Quintana | SP (RP) | ChN | 31 | |
| Stephen Strasburg | SP | Was | 32 | August 15, 2020:15 Day IL-Abdomen |
| Adam Wainwright | SP | StL | 39 | |
| Archie Bradley | RP | Cin | 28 | |
| Josh Hader | RP | Mil | 26 | |
| Jose Leclerc | RP | Tex | 26 | July 27, 2020:60 Day IL-Strained teres major, right shoulder |
| Carlos Martinez | RP (SP) | StL | 29 | September 24, 2020:10 Day IL-Strained left oblique |