| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Joey Bart | C | Pit | 28 | |
| Logan O'Hoppe | C | LAA | 25 | |
| Joshua Bell | 1B | Was | 32 | |
| Freddie Freeman | 1B | LAD | 35 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Willi Castro | 2B (SS,3B) | Min | 28 | April 24, 2025:10 Day IL |
| Andrés Gimenez | 2B | Tor | 26 | |
| Gabriel Arias | SS (2B,3B) | Cle | 25 | |
| Javier Baez | SS (3B,OF) | Det | 32 | |
| Jose Caballero | SS (3B,OF) | TB | 28 | |
| Francisco Lindor | SS | NYN | 31 | |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Austin Riley | 3B | Atl | 28 | |
| Jordan Westburg | 3B (2B) | Bal | 26 | April 28, 2025:10 Day IL |
| Alec Burleson | OF (1B) | StL | 26 | |
| Lawrence Butler | OF | Oak | 24 | |
| Jarren Duran | OF | Bos | 28 | |
| Sal Frelick | OF | Mil | 25 | |
| Parker Meadows | OF | Det | 25 | March 24, 2025:60 Day IL |
| Kameron Misner | OF | TB | N/A | |
| George Springer | OF | Tor | 35 | |
| Daulton Varsho | OF | Tor | 28 | |
| Matt Wallner | OF | Min | 27 | April 17, 2025:10 Day IL |
| Chris Bassitt | SP | Tor | 36 | |
| Dylan Cease | SP | SD | 29 | |
| Logan Gilbert | SP | Sea | 27 | April 26, 2025:15 Day IL |
| Ryan Pepiot | SP | TB | 27 | |
| Freddy Peralta | SP | Mil | 28 | |
| Brandon Pfaadt | SP | Ari | 26 | |
| Joe Ryan | SP | Min | 28 | |
| Blake Snell | SP | LAD | 32 | April 06, 2025:15 Day IL-Ab strain |
| Anthony Bender | RP | Mia | 30 | |
| Jhoan Duran | RP | Min | 27 | |
| Will Vest | RP | Det | 29 |