| Week | Add | Drop |
| Pre-Season |
Round 1: C Gary Sanchez - Mil Round 2: C Elias Diaz - Col |
Round 1: SP Matt Manning - Det Round 2: OF TJ Friedl - Cin |
| Week 2 |
Round 1: SP Kyle Gibson - StL | |
| Week 3 |
Round 1: SP Matt Manning - Det | |
| Week 4 |
Round 1: 1B LaMonte Wade Jr - SF Round 2: 2B Thomas Saggese - StL |
Round 1: SP Braxton Garrett - Mia Round 2: SP Tylor Megill - NYN |
| Week 5 |
Round 1: 3B Orelvis Martinez - Tor Round 2: SS Matt Shaw - ChN |
Round 1: RP David Robertson - Tex Round 2: RP Yuki Matsui - SD |
| Week 6 |
Round 1: 2B Connor Norby - Bal Round 2: SP Chris Paddack - Min |
Round 1: 2B Thomas Saggese - StL Round 2: SP Griffin Canning - LAA |
| 1st Team | 2nd Team |
| Pre-Season | |
| Al Davis Cajuns | New York City MSG |
|
SP
Jeffrey Springs
TB |
Round 8, 11th Pick (SP Jordan Wicks ChN) |
| Week 4 | |
| Al Davis Cajuns | New York City MSG |
|
RP
Craig Kimbrel
Bal 3B Ryan McMahon Col OF Teoscar Hernández LAD 1B Ryan Mountcastle Bal 1B Josh Naylor Cle SS Jeremy Pena Hou |
RP
David Robertson
Tex 1B Kris Bryant Col SP Kenta Maeda Det SP Dean Kremer Bal 3B Coby Mayo Bal OF James Wood Was |
| Week 6 | |
| Al Davis Cajuns | New York City MSG |
|
3B
Alex Bregman
Hou OF Kyle Tucker Hou SP Dean Kremer Bal |
SP
Edward Cabrera
Mia OF Corbin Carroll Ari OF Evan Carter Tex |