| Week | Add | Drop |
| Pre-Season |
Round 1: OF Walker Jenkins - Min Round 2: SP Jose Quintana - NYN | |
| Week 1 |
Round 1: RP David Robertson - Tex Round 2: RP Ronel Blanco - Hou | |
| Week 2 |
Round 1: SP Paul Blackburn - Oak Round 2: SP Dean Kremer - Bal |
Round 2: DH Mitch Garver - Sea |
| Week 3 |
Round 1: SP Reynaldo Lopez - Atl Round 2: C Ivan Herrera - StL |
Round 1: OF Matt Wallner - Min Round 2: RP Jose Leclerc - Tex |
| Week 4 |
Round 1: SP Edward Cabrera - Mia Round 2: RP José Alvarado - Phi |
Round 1: 3B Maikel Garcia - KC Round 2: 1B Jose Abreu - Hou |
| Week 5 |
Round 2: OF Mark Canha - Det |
Round 2: C Ivan Herrera - StL |
| Week 6 |
Round 1: C Danny Jansen - Tor Round 2: SP Trevor Williams - Was |
Round 1: SP Jose Quintana - NYN Round 2: OF Walker Jenkins - Min |
| 1st Team | 2nd Team |
| Pre-Season | |
| New York City MSG | Fightin Phils |
|
Round 9, 11th Pick (3B Yoan Moncada ChA) |
Round 11, 5th Pick (3B Maikel Garcia KC) Round 12, 5th Pick (SP Nick Lodolo Cin) Round 16, 5th Pick (SP Clarke Schmidt NYA) |
| Pre-Season | |
| New York City MSG | Fight at the Bat Rack |
|
Round 16, 5th Pick (SP Clarke Schmidt NYA) Round 16, 11th Pick (SP Martin Perez Pit) |
Round 15, 1st Pick (RP Mason Miller Oak) |
| Pre-Season | |
| New York City MSG | Bleacher Bums |
|
1B
Matt Olson
Atl OF Josh Lowe TB SP Logan Webb SF Round 15, 11th Pick (SP Andrew Abbott Cin) |
3B
Austin Riley
Atl OF Evan Carter Tex Round 4, 3rd Pick (3B Coby Mayo Bal) Round 14, 3rd Pick (SP Kenta Maeda Det) |
| Pre-Season | |
| New York City MSG | Fightin Phils |
|
Round 7, 11th Pick (C Jonah Heim Tex) |
OF
James Wood
Was Round 11, 9th Pick (SP Cristopher Sanchez Phi) |
| Pre-Season | |
| New York City MSG | Poker in the Rear |
|
Round 15, 1st Pick (RP Mason Miller Oak) Round 15, 5th Pick (SS Geraldo Perdomo Ari) Round 15, 7th Pick (3B Mark Vientos NYN) |
Round 13, 5th Pick (1B Kris Bryant Col) |
| Pre-Season | |
| New York City MSG | Bleacher Bums |
|
OF
Nolan Jones
Col |
Round 3, 3rd Pick (SP Freddy Peralta Mil) Round 6, 3rd Pick (2B Edouard Julien Min) |
| Pre-Season | |
| New York City MSG | Poker in the Rear |
|
Round 17, 11th Pick (OF Brenton Doyle Col) Round 18, 11th Pick (SP Chase Silseth LAA) Round 19, 11th Pick (C Ryan Jeffers Min) |
Round 15, 9th Pick (RP Jose Leclerc Tex) |
| Pre-Season | |
| New York City MSG | Buffalo Horseheads |
|
Round 2, 11th Pick (2B Colt Keith Det) Round 3, 11th Pick (SP Carlos Rodon NYA) |
C
Danny Jansen
Tor |
| Pre-Season | |
| New York City MSG | Vanilla Gorillas |
|
Round 5, 11th Pick (1B Jeimer Candelario Cin) |
Round 15, 7th Pick (3B Mark Vientos NYN) |
| Pre-Season | |
| New York City MSG | Fightin Phils |
|
Round 6, 11th Pick (OF Jarred Kelenic Atl) |
Round 15, 5th Pick (SS Geraldo Perdomo Ari) |
| Pre-Season | |
| New York City MSG | Al Davis Cajuns |
|
Round 8, 11th Pick (SP Jordan Wicks ChN) |
SP
Jeffrey Springs
TB |
| Pre-Season | |
| New York City MSG | Popcorn Obliques |
|
C
Will Smith
LAD |
OF
Nolan Jones
Col Round 2, 6th Pick (1B Nate Lowe Tex) |
| Pre-Season | |
| New York City MSG | Fightin Phils |
|
SP
Aaron Nola
Phi |
OF
Josh Lowe
TB |
| Week 4 | |
| New York City MSG | Al Davis Cajuns |
|
RP
David Robertson
Tex 1B Kris Bryant Col SP Kenta Maeda Det SP Dean Kremer Bal 3B Coby Mayo Bal OF James Wood Was |
RP
Craig Kimbrel
Bal 3B Ryan McMahon Col OF Teoscar Hernández LAD 1B Ryan Mountcastle Bal 1B Josh Naylor Cle SS Jeremy Pena Hou |
| Week 6 | |
| New York City MSG | Al Davis Cajuns |
|
SP
Edward Cabrera
Mia OF Corbin Carroll Ari OF Evan Carter Tex |
3B
Alex Bregman
Hou OF Kyle Tucker Hou SP Dean Kremer Bal |