| Week | Add | Drop |
| Pre-Season |
Round 1: 3B Oliver Dunn - Mil Round 2: C Danny Jansen - TB Round 3: 1B Ty France - Min Round A: SS Sebastian Walcott - Tex Round B: SP Bubba Chandler - Pit |
Round A: 3B Josh Smith - Tex |
| Week 1 |
Round 1: SP Landen Roupp - SF Round 2: C Kyle Higashioka - Tex Round 3: 3B Ernie Clement - Tor | |
| Week 2 |
Round 1: RP Dennis Santana - Pit Round 2: SS Isiah Kiner-Falefa - Pit Round 3: RP Anthony Bender - Mia |
Round 1: C Kyle Higashioka - Tex Round 2: C Danny Jansen - TB Round 3: SS Brayan Rocchio - Cle |
| Week 3 |
Round 1: OF Sal Frelick - Mil Round 3: SP Tobias Myers - Mil |
Round 1: 3B Oliver Dunn - Mil Round 3: RP Dennis Santana - Pit |
| Week 4 |
Round 1: RP Emilio Pagan - Cin Round 3: OF Chandler Simpson - TB |
Round 1: SP Landen Roupp - SF Round 2: 3B Ernie Clement - Tor Round 3: OF Garrett Mitchell - Mil |
| Week 5 |
Round 2: SP Hayden Wesneski - Hou Round 3: RP Will Vest - Det |
Round 2: OF Sal Frelick - Mil Round 3: 1B Colt Keith - Det |
| Week 6 |
Round 2: SS Javier Baez - Det |
Round 2: RP Alexis Diaz - Cin |
| 1st Team | 2nd Team |
| Pre-Season | |
| Spokane Indians | Brooklyn Dodgers |
|
Round 2, 6th Pick (SP Bryan Woo Sea) |
SP
Yoshinobu Yamamoto
LAD |
| Pre-Season | |
| Spokane Indians | Warning Track Power |
|
Round 3, 6th Pick (3B Isaac Paredes Hou) Round 4, 6th Pick (RP Andres Munoz Sea) Round 5, 6th Pick (SP Jared Jones Pit) |
SP
Chris Sale
Atl SP Michael King SD SP Spencer Schwellenbach Atl |
| Pre-Season | |
| Spokane Indians | Dodgers |
|
1B
Josh Naylor
Ari |
SP
Spencer Strider
Atl |
| Pre-Season | |
| Spokane Indians | Dodgers |
|
OF
Anthony Santander
Tor |
Round 5, 10th Pick (RP Kenley Jansen LAA) |
| Pre-Season | |
| Spokane Indians | Chattanooga Lookouts |
|
SP
Spencer Schwellenbach
Atl |
Round 4, 4th Pick (RP Alexis Diaz Cin) |