| Week | Add | Drop |
| Pre-Season |
Round 1: 1B Jonathan Aranda - TB Round 2: OF Mike Yastrzemski - SF Round 3: OF Jung Hoo Lee - SF |
Round 2: OF Jerar Encarnación - SF |
| Week 1 |
Round 1: SP José Soriano - LAA | |
| Week 2 |
Round 2: SS Kyren Paris - LAA |
Round 2: C Ryan Jeffers - Min |
| Week 4 |
Round 1: C Drake Baldwin - Atl |
Round 1: 3B Joey Ortiz - Mil |
| Week 5 |
Round 2: 2B Jonathan India - KC |
| 1st Team | 2nd Team |
| Pre-Season | |
| Surprise Saguaros | Built 4 Speed |
|
SP
Cole Ragans
KC |
Round 4, 2nd Pick (3B Isaac Paredes Hou) |
| Pre-Season | |
| Surprise Saguaros | Twins Rock |
|
OF
Teoscar Hernández
LAD |
Round 5, 6th Pick (SP Shane Baz TB) |
| Pre-Season | |
| Surprise Saguaros | Whiz Kids |
|
Round 2, 1st Pick (SP Tyler Glasnow LAD) Round 4, 1st Pick (SP Seth Lugo KC) |
OF
Teoscar Hernández
LAD OF Cody Bellinger NYA |
| Pre-Season | |
| Surprise Saguaros | My Bad |
|
Round 1, 10th Pick (RP Robert Suarez SD) |
OF
Michael Harris II
Atl |
| Pre-Season | |
| Surprise Saguaros | My Bad |
|
SS
Corey Seager
Tex |
SS
Bo Bichette
Tor Round 4, 11th Pick (2B Jonathan India KC) Round 1, 10th Pick (RP Robert Suarez SD) |
| Pre-Season | |
| Surprise Saguaros | My Bad |
|
Round 7, 1st Pick (SP Clay Holmes NYN) Round 10, 1st Pick (1B Bryce Eldridge SF) |
OF
Evan Carter
Tex 2B Christian Moore LAA |
| Pre-Season | |
| Surprise Saguaros | DRIVEWAY DRINKERS |
|
Round 1, 10th Pick (RP Robert Suarez SD) |
SP
Gerrit Cole
NYA |
| Week 5 | |
| Surprise Saguaros | The Plantation |
|
1B
Josh Naylor
Ari C Alejandro Kirk Tor |
1B
Jake Burger
Tex SP Framber Valdez Hou |
| Week 5 | |
| Surprise Saguaros | DRIVEWAY DRINKERS |
|
SP
Shane Baz
TB |
2B
Marcus Semien
Tex |