*=Defensive Player of the Week
| Rank | Score | Week | Proteam | Opponent | Breakdown |
| 1. | 19.00 | Week 04, 2019 | Pit | CinCin | 4 Tackles, 2 Assists, 2.5 Sacks, 1 FF |
| 1. | 19.00 | Week 04, 2016 | Pit | KCKC | 6 Tackles, 3.0 Sacks, 1 PD |
| 3. | 18.00 | Week 04, 2017 | Pit | @Bal@Bal | 3 Tackles, 1 Assist, 2.0 Sacks, 1 FF, 1 Fum Rcvy |
| 4. | 17.00 | Week 18, 2022 | Pit | CleCle | 3 Tackles, 5 Assists, 2.0 Sacks, 1 PD |
| 5. | 16.00 | Week 16, 2022 | Pit | LVLV | 4 Tackles, 3 Assists, 2.0 Sacks, 1 PD |
| 5. | 16.00 | Week 01, 2021 | Pit | @BUF@BUF | 2 Tackles, 2 Assists, 1.0 Sack, 1 FF, 1 Fum Rcvy, 2 PD |
| 7. | 15.00 | Week 14, 2013 | Pit | MiaMia | 7 Tackles, 3 Assists, 1.0 Sack, 1 PD |
| 8. | 14.00 | Week 12, 2017 | Pit | GBGB | 3 Tackles, 3 Assists, 2.0 Sacks |
| 8. | 14.00 | Week 04, 2015 | Pit | BalBal | 7 Tackles, 1.0 Sack, 1 FF |
| 10. | 13.00 | Week 14, 2024 | Pit | CleCle | 3 Tack, 2 Ass, 2.00 Sack |
| 10. | 13.00 | Week 10, 2021 | Pit | DETDET | 3 Tackles, 2 Assists, 2.0 Sacks |
| 10. | 13.00 | Week 06, 2021 | Pit | SEASEA | 6 Tackles, 3 Assists, 1.0 Sack |
| 13. | 12.00 | Week 12, 2021 | Pit | @CIN@CIN | 2 Tackles, 6 Assists, 1.0 Sack |
| 13. | 12.00 | Week 11, 2018 | Pit | @Jac@Jac | 4 Tackles, 1 Assist, 1.0 Sack, 1 Fum Rcvy |
| 13. | 12.00 | Week 16, 2017 | Pit | @Hou@Hou | 3 Tackles, 1 Assist, 2.0 Sacks |
| 13. | 12.00 | Week 17, 2014 | Pit | CinCin | 6 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 17. | 11.00 | Week 10, 2024 | Pit | @Was@Was | 2 Tack, 2.00 Sack, 1 PD |
| 17. | 11.00 | Week 11, 2022 | Pit | CinCin | 4 Tackles, 3 Assists, 1.0 Sack |
| 17. | 11.00 | Week 13, 2019 | Pit | CleCle | 3 Tackles, 3 Assists, 0.5 Sack, 1 Fum Rcvy |
| 17. | 11.00 | Week 08, 2019 | Pit | MiaMia | 3 Tackles, 3 Assists, 1.0 Sack, 1 PD |
| 17. | 11.00 | Week 10, 2018 | Pit | CarCar | 2 Tackles, 1 Assist, 2.0 Sacks |
| 17. | 11.00 | Week 01, 2018 | Pit | @Cle@Cle | 5 Tackles, 2 Assists, 1.0 Sack |
| 17. | 11.00 | Week 11, 2017 | Pit | TenTen | 2 Tackles, 1 Assist, 2.0 Sacks |
| 24. | 10.00 | Week 13, 2024 | Pit | @Cin@Cin | 3 Tack, 2 Ass, 1.00 Sack, 1 PD |
| 24. | 10.00 | Week 04, 2024 | Pit | @Ind@Ind | 2 Tack, 4 Ass, 1.00 Sack |
| 24. | 10.00 | Week 14, 2023 | Pit | NENE | 5 Tackles, 1 Assist, 1.0 Sack |
| 24. | 10.00 | Week 18, 2021 | Pit | @BAL@BAL | 6 Tackles, 1.0 Sack |
| 24. | 10.00 | Week 17, 2021 | Pit | CLECLE | 4 Tackles, 1.0 Sack, 2 PD |
| 24. | 10.00 | Week 16, 2021 | Pit | @KC@KC | 3 Tackles, 3 Assists, 1.0 Sack |
| 24. | 10.00 | Week 12, 2019 | Pit | @Cin@Cin | 2 Tackles, 4 Assists, 1.0 Sack |
| 24. | 10.00 | Week 17, 2018 | Pit | CinCin | 2 Tackles, 2.0 Sacks |
| 24. | 10.00 | Week 02, 2015 | Pit | SFSF | 5 Tackles, 1 Assist, 1.0 Sack |
| 24. | 10.00 | Week 16, 2014 | Pit | KCKC | 2 Tackles, 2 Assists, 1.5 Sacks |
| 24. | 10.00 | Week 10, 2014 | Pit | @NYJ@NYJ | 4 Tackles, 2 Assists, 1.0 Sack |
| 24. | 10.00 | Week 10, 2013 | Pit | BufBuf | 5 Tackles, 1 Assist, 1.0 Sack |
| 36. | 9.00 | Week 15, 2022 | Pit | @Car@Car | 1 Tackle, 2 Assists, 1.5 Sacks |
| 36. | 9.00 | Week 13, 2022 | Pit | @Atl@Atl | 2 Tackles, 2 Assists, 1.0 Sack, 1 PD |
| 36. | 9.00 | Week 05, 2022 | Pit | @Buf@Buf | 1 Tackle, 4 Assists, 1 FF, 1 PD |
| 36. | 9.00 | Week 01, 2022 | Pit | @CIN@CIN | 2 Tackles, 1.0 Sack, 1 Fum Rcvy |
| 36. | 9.00 | Week 16, 2020 | Pit | INDIND | 2 Tackles, 3 Assists, 1.0 Sack |
| 36. | 9.00 | Week 17, 2019 | Pit | @Bal@Bal | 3 Tackles, 1 Assist, 1.0 Sack, 1 PD |
| 36. | 9.00 | Week 15, 2019 | Pit | BufBuf | 5 Tackles, 3 Assists, 1 PD |
| 36. | 9.00 | Week 10, 2019 | Pit | LARLAR | 2 Tackles, 1 Assist, 1.0 Sack, 2 PD |
| 36. | 9.00 | Week 05, 2018 | Pit | AtlAtl | 2 Tackles, 1 Assist, 1.5 Sacks |
| 36. | 9.00 | Week 12, 2013 | Pit | @Cle@Cle | 1 Tackle, 1 Assist, 1.0 Sack, 1 Fum Rcvy |
| 36. | 9.00 | Week 09, 2013 | Pit | @NE@NE | 2 Tackles, 3 Assists, 1.0 Sack |
| 36. | 9.00 | Week 05, 2011 | Pit | TenTen | 2 Tackles, 1.0 Sack, 1 FF |
| 48. | 8.00 | Week 12, 2024 | Pit | @Cle@Cle | 1 Tack, 5 Ass, 2 PD |
| 48. | 8.00 | Week 06, 2024 | Pit | @LV @LV | 3 Tack, 1 Ass, 1.00 Sack |
| 48. | 8.00 | Week 03, 2024 | Pit | LACLAC | 3 Tack, 1 Ass, 1.00 Sack |